Supramolecular Brake for Slowing Fentanyl Into Brain to Ameliorate Its Therapeutic Outcome

Supramolecular Brake for Slowing Fentanyl Into Brain to Ameliorate Its Therapeutic Outcome

ABSTRACT Fentanyl (Fen) analogs, clinically used anesthetic adjuvants, are often trouble with overdose‐induced adverse effects due to rapid entry into the brain plus short retention time. Advanced approaches that can relieve related life‐threatening symptoms without compromising their anesthetic eff...

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Main Authors: Longming Chen, Kaili Jiang, Yuanyuan Liu, Mengran Song, Yibo Zhao, Chengyang Tian, Yahan Zhang, Ziliang Zhang, Xiang Yu, Junhai Xiao, Junyi Chen, Zheng Yong, Chunju Li, Qingbin Meng
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:SmartMat
Subjects:
fentanyl
host–guest complexation
supramolecular brake
terphen[3]arene sulfate
therapeutic outcome
Online Access:https://doi.org/10.1002/smm2.70020
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