A Huluwa phosphorylation switch regulates embryonic axis induction

A Huluwa phosphorylation switch regulates embryonic axis induction

Abstract Embryonic axis formation is essential for patterning and morphogenesis in vertebrates and is tightly regulated by the dorsal organizer. Previously, we demonstrated that maternally derived Huluwa (Hwa) acts as a dorsal determinant, dictating axis formation by activating β-catenin signaling i...

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Main Authors: Yao Li, Yun Yan, Bo Gong, Qianwen Zheng, Haiyan Zhou, Jiarui Sun, Mingpeng Li, Zhao Wang, Yaohui Li, Yunjing Wan, Weixi Chen, Shiqian Qi, Xianming Mo, Anming Meng, Bo Xiang, Jing Chen
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54450-4
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