Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model
Background. Nerve stimulation can facilitate correct needle placement in peripheral regional anesthesia. The aim of this study was to determine whether the high threshold current is associated with reduced nerve injury due to fewer needle-nerve contacts compared with low current. Methods. In anaesth...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Anesthesiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2011/591851 |
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| author | T. Steinfeldt J. Graf J. Schneider W. Nimphius E. Weihe A. Borgeat H. Wulf T. Wiesmann |
| author_facet | T. Steinfeldt J. Graf J. Schneider W. Nimphius E. Weihe A. Borgeat H. Wulf T. Wiesmann |
| author_sort | T. Steinfeldt |
| collection | DOAJ |
| description | Background. Nerve stimulation can facilitate correct needle placement in peripheral regional anesthesia. The aim of this study was to determine whether the high threshold current is associated with reduced nerve injury due to fewer needle-nerve contacts compared with low current. Methods. In anaesthetized pigs, thirty-two nerves of the brachial plexus underwent needle placement at low (0.2 mA) or high current (1.0 mA). The occurrence of needle-nerve contact was recorded. After 48 hours, the nerves were analyzed for occurrence of histological changes. Nerve injury was scored ranging from 0 (no injury) to 4 (severe injury). Results. The frequency of needle-nerve contact was 94% at low compared to 6% at high current. The score was significantly higher at low (median [interquartile range] 2.0 [1.0-2.0]) compared to high current (0.0 [0.0-1.0] P=.001). Conclusions. Inflammatory responses were directly related to needle-nerve contacts. Hence, posttraumatic inflammation may be diminished using higher current for nerve localization. |
| format | Article |
| id | doaj-art-9e55fd1c367f43b8818de614fc64003d |
| institution | Kabale University |
| issn | 1687-6962 1687-6970 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anesthesiology Research and Practice |
| spelling | doaj-art-9e55fd1c367f43b8818de614fc64003d2025-02-03T01:25:33ZengWileyAnesthesiology Research and Practice1687-69621687-69702011-01-01201110.1155/2011/591851591851Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig ModelT. Steinfeldt0J. Graf1J. Schneider2W. Nimphius3E. Weihe4A. Borgeat5H. Wulf6T. Wiesmann7Department of Anaesthesiology and Intensive Care Therapy, University Hospital Giessen-Marburg, Faculty of Medicine, Philipps University Marburg, Campus Marburg, Baldingerstraβe, 35032 Marburg, GermanyLufthansa AG, Aero Medical Center, Lufthansa Basis, Tor 21, 60546 Frankfurt am Main, GermanyDepartment of Anaesthesiology and Intensive Care Therapy, University Hospital Giessen-Marburg, Faculty of Medicine, Philipps University Marburg, Campus Marburg, Baldingerstraβe, 35032 Marburg, GermanyDepartment of Anaesthesiology and Intensive Care Therapy, University Hospital Giessen-Marburg, Faculty of Medicine, Philipps University Marburg, Campus Marburg, Baldingerstraβe, 35032 Marburg, GermanyFaculty of Medicine, Institute of Anatomy and Cell Biology, Philipps University Marburg, Robert-Koch Straβe 8, 35032 Marburg, GermanyDepartment of Anaesthesia, Faculty of Medicine, Balgrist University Hospital, University of Zurich, Forchstraβe 340, 8008 Zurich, SwitzerlandDepartment of Anaesthesiology and Intensive Care Therapy, University Hospital Giessen-Marburg, Faculty of Medicine, Philipps University Marburg, Campus Marburg, Baldingerstraβe, 35032 Marburg, GermanyDepartment of Anaesthesiology and Intensive Care Therapy, University Hospital Giessen-Marburg, Faculty of Medicine, Philipps University Marburg, Campus Marburg, Baldingerstraβe, 35032 Marburg, GermanyBackground. Nerve stimulation can facilitate correct needle placement in peripheral regional anesthesia. The aim of this study was to determine whether the high threshold current is associated with reduced nerve injury due to fewer needle-nerve contacts compared with low current. Methods. In anaesthetized pigs, thirty-two nerves of the brachial plexus underwent needle placement at low (0.2 mA) or high current (1.0 mA). The occurrence of needle-nerve contact was recorded. After 48 hours, the nerves were analyzed for occurrence of histological changes. Nerve injury was scored ranging from 0 (no injury) to 4 (severe injury). Results. The frequency of needle-nerve contact was 94% at low compared to 6% at high current. The score was significantly higher at low (median [interquartile range] 2.0 [1.0-2.0]) compared to high current (0.0 [0.0-1.0] P=.001). Conclusions. Inflammatory responses were directly related to needle-nerve contacts. Hence, posttraumatic inflammation may be diminished using higher current for nerve localization.http://dx.doi.org/10.1155/2011/591851 |
| spellingShingle | T. Steinfeldt J. Graf J. Schneider W. Nimphius E. Weihe A. Borgeat H. Wulf T. Wiesmann Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model Anesthesiology Research and Practice |
| title | Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model |
| title_full | Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model |
| title_fullStr | Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model |
| title_full_unstemmed | Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model |
| title_short | Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model |
| title_sort | histological consequences of needle nerve contact following nerve stimulation in a pig model |
| url | http://dx.doi.org/10.1155/2011/591851 |
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