Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557)
Prior to preparation of CRM candidate of chloramphenicol in methanol with a concentration of 100 mg/L, two independent methods including mass balance (MB) and quantitative nuclear magnetic resonance (qNMR) were employed to precisely measure the mass fraction of pure chloramphenicol materials. The ma...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | International Journal of Analytical Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2016/2348257 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832566773922136064 |
|---|---|
| author | Mengrui Yang Min Wang Jian Zhou Yinqing Song Tongtong Wang |
| author_facet | Mengrui Yang Min Wang Jian Zhou Yinqing Song Tongtong Wang |
| author_sort | Mengrui Yang |
| collection | DOAJ |
| description | Prior to preparation of CRM candidate of chloramphenicol in methanol with a concentration of 100 mg/L, two independent methods including mass balance (MB) and quantitative nuclear magnetic resonance (qNMR) were employed to precisely measure the mass fraction of pure chloramphenicol materials. The mass fraction was assigned to be 99.8% with uncertainty of 0.3%. Homogeneity testing and stability study of chloramphenicol in methanol were examined by using high performance liquid chromatography. Additionally, the uncertainties originating from the process of CRM development were comprehensively evaluated. The experimental results indicate that the property value of this CRM is homogeneous and stable at 4°C for at least six months. The new CRM (GBW(E)082557) can be applicable to calibration of instrument and assurance of accuracy and comparability of results in routine measurement. |
| format | Article |
| id | doaj-art-9e524a9cc2b24548b639d82060095a70 |
| institution | Kabale University |
| issn | 1687-8760 1687-8779 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Analytical Chemistry |
| spelling | doaj-art-9e524a9cc2b24548b639d82060095a702025-02-03T01:03:21ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792016-01-01201610.1155/2016/23482572348257Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557)Mengrui Yang0Min Wang1Jian Zhou2Yinqing Song3Tongtong Wang4Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaPrior to preparation of CRM candidate of chloramphenicol in methanol with a concentration of 100 mg/L, two independent methods including mass balance (MB) and quantitative nuclear magnetic resonance (qNMR) were employed to precisely measure the mass fraction of pure chloramphenicol materials. The mass fraction was assigned to be 99.8% with uncertainty of 0.3%. Homogeneity testing and stability study of chloramphenicol in methanol were examined by using high performance liquid chromatography. Additionally, the uncertainties originating from the process of CRM development were comprehensively evaluated. The experimental results indicate that the property value of this CRM is homogeneous and stable at 4°C for at least six months. The new CRM (GBW(E)082557) can be applicable to calibration of instrument and assurance of accuracy and comparability of results in routine measurement.http://dx.doi.org/10.1155/2016/2348257 |
| spellingShingle | Mengrui Yang Min Wang Jian Zhou Yinqing Song Tongtong Wang Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) International Journal of Analytical Chemistry |
| title | Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) |
| title_full | Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) |
| title_fullStr | Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) |
| title_full_unstemmed | Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) |
| title_short | Characterization and Uncertainty Assessment of a Certified Reference Material of Chloramphenicol in Methanol (GBW(E)082557) |
| title_sort | characterization and uncertainty assessment of a certified reference material of chloramphenicol in methanol gbw e 082557 |
| url | http://dx.doi.org/10.1155/2016/2348257 |
| work_keys_str_mv | AT mengruiyang characterizationanduncertaintyassessmentofacertifiedreferencematerialofchloramphenicolinmethanolgbwe082557 AT minwang characterizationanduncertaintyassessmentofacertifiedreferencematerialofchloramphenicolinmethanolgbwe082557 AT jianzhou characterizationanduncertaintyassessmentofacertifiedreferencematerialofchloramphenicolinmethanolgbwe082557 AT yinqingsong characterizationanduncertaintyassessmentofacertifiedreferencematerialofchloramphenicolinmethanolgbwe082557 AT tongtongwang characterizationanduncertaintyassessmentofacertifiedreferencematerialofchloramphenicolinmethanolgbwe082557 |