Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway

Phase-dependent iron depletion differentially regulates the niche of intestinal stem cells in experimental colitis via ERK/STAT3 signaling pathway

IntroductionUlcerative colitis (UC) is a global gastrointestinal disease, which is mainly caused by both dysfunctional epithelial barrier and inflammation response. Iron is a critical fundamental element for both the maintenance of homeostasis and the mediation of inflammation in many tissues. Howev...

Full description

Saved in:
Bibliographic Details
Main Authors: Shubin Wang, Xiangjun Liu, Lu Xu, Jinyi Lang, Dengqun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
deferoxamine
iron
intestinal stem cell
organoid
colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537651/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items