Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration

Electrochemiluminescence biosensor is an analytical method combining electrochemiluminescence technology with biosensor. Using nanomaterials as electrochemical luminescence sensor platform can not only immobilize a large number of biomolecules but also improve the performance of the sensor to realiz...

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Main Authors: Tengfei Ma, Hao Wu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2020/5474506
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author Tengfei Ma
Hao Wu
author_facet Tengfei Ma
Hao Wu
author_sort Tengfei Ma
collection DOAJ
description Electrochemiluminescence biosensor is an analytical method combining electrochemiluminescence technology with biosensor. Using nanomaterials as electrochemical luminescence sensor platform can not only immobilize a large number of biomolecules but also improve the performance of the sensor to realize the supersensitive detection of biomacromolecules. Although these methods have high sensitivity for bioanalysis, there are still some shortcomings which limit the practical application. Therefore, this paper discusses the development of functional gold nanomaterials industry and its application in chemiluminescence bioanalysis. In this paper, two methods of synthesizing luminescent functional gold nanomaterials at room temperature were studied by using chemiluminescent reagents as reducing agent and protective agent. Based on luminescent functionalized gold nanoparticles, immunoassay and DNA bioanalysis probes were constructed, and their applications in chemiluminescence and electrochemiluminescence bioanalysis were discussed. Finally, the simulation results show that the relative deviation between the experimental results and the existing clinical methods is less than 17%. The sensor has good stability and selectivity and can be used for the determination of CEA in human serum. The gold nanomaterials synthesized by further research have excellent chemiluminescence activity and can be used to label biomolecules and prepare biological probes. This article aims to explore the application of chemical methods in the transformation of new industries, to achieve breakthroughs in new products in industrial innovation, and to achieve the cross-fusion of management science and engineering disciplines and chemical disciplines. The industrial development of derivative functionalized gold nanomaterials has broad application prospects in biological analysis.
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spelling doaj-art-9e32e50d755243c398b1d45cf4b3e21e2025-02-03T01:28:35ZengWileyJournal of Chemistry2090-90632090-90712020-01-01202010.1155/2020/54745065474506Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban AgglomerationTengfei Ma0Hao Wu1Faculty of Management and Economics, Kunming University of Science and Technology, Kunming 650093, Yunnan, ChinaFaculty of Materials Science and Engineering, Kunming University of Science and Technology, Kunming 650093, Yunnan, ChinaElectrochemiluminescence biosensor is an analytical method combining electrochemiluminescence technology with biosensor. Using nanomaterials as electrochemical luminescence sensor platform can not only immobilize a large number of biomolecules but also improve the performance of the sensor to realize the supersensitive detection of biomacromolecules. Although these methods have high sensitivity for bioanalysis, there are still some shortcomings which limit the practical application. Therefore, this paper discusses the development of functional gold nanomaterials industry and its application in chemiluminescence bioanalysis. In this paper, two methods of synthesizing luminescent functional gold nanomaterials at room temperature were studied by using chemiluminescent reagents as reducing agent and protective agent. Based on luminescent functionalized gold nanoparticles, immunoassay and DNA bioanalysis probes were constructed, and their applications in chemiluminescence and electrochemiluminescence bioanalysis were discussed. Finally, the simulation results show that the relative deviation between the experimental results and the existing clinical methods is less than 17%. The sensor has good stability and selectivity and can be used for the determination of CEA in human serum. The gold nanomaterials synthesized by further research have excellent chemiluminescence activity and can be used to label biomolecules and prepare biological probes. This article aims to explore the application of chemical methods in the transformation of new industries, to achieve breakthroughs in new products in industrial innovation, and to achieve the cross-fusion of management science and engineering disciplines and chemical disciplines. The industrial development of derivative functionalized gold nanomaterials has broad application prospects in biological analysis.http://dx.doi.org/10.1155/2020/5474506
spellingShingle Tengfei Ma
Hao Wu
Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
Journal of Chemistry
title Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
title_full Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
title_fullStr Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
title_full_unstemmed Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
title_short Industry Development of Derivative Functionalized Gold Nanomaterials and Their Application in Chemiluminescence Bioanalysis: Based on the Industrial Practice of China's Central Yunnan Urban Agglomeration
title_sort industry development of derivative functionalized gold nanomaterials and their application in chemiluminescence bioanalysis based on the industrial practice of china s central yunnan urban agglomeration
url http://dx.doi.org/10.1155/2020/5474506
work_keys_str_mv AT tengfeima industrydevelopmentofderivativefunctionalizedgoldnanomaterialsandtheirapplicationinchemiluminescencebioanalysisbasedontheindustrialpracticeofchinascentralyunnanurbanagglomeration
AT haowu industrydevelopmentofderivativefunctionalizedgoldnanomaterialsandtheirapplicationinchemiluminescencebioanalysisbasedontheindustrialpracticeofchinascentralyunnanurbanagglomeration