Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression

Predicting cisplatin response in cholangiocarcinoma patients using chromosome pattern and related gene expression

Abstract Cholangiocarcinoma (CCA) is a prevalent bile duct cancer with limited treatment options. Cisplatin-based chemotherapy is a common approach, but response rates vary. Recently, chromosome aberrations have emerged as predictors of chemotherapy response in various malignancies. This study aimed...

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Main Authors: Sutheemon Techa-ay, Sasithorn Watcharadetwittaya, Raksawan Deenonpoe, Kitti Intuyod, Waleeporn Kaewlert, Anchalee Techasen, Watcharin Loilome, Poramate Klanrit, Manida Suksawat, Kwanjira Chaleekan, Sirinya Sitthirak, Malinee Thanee
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-06851-8
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