Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant
We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a neurotoxin-producing Clostridium botulinum an...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Journal of Pediatrics: Clinical Practice |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S295054102500002X |
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| author | Barbara Schaub, MD Carolyn Luhman-Lunt, MD Andrea Ott, MD Maren Krüger, DSc Martin Skiba, PhD Sylvia Worbs, PhD Brigitte G. Dorner, PhD Michael Buettcher, MD Martin B. Dorner, PhD |
| author_facet | Barbara Schaub, MD Carolyn Luhman-Lunt, MD Andrea Ott, MD Maren Krüger, DSc Martin Skiba, PhD Sylvia Worbs, PhD Brigitte G. Dorner, PhD Michael Buettcher, MD Martin B. Dorner, PhD |
| author_sort | Barbara Schaub, MD |
| collection | DOAJ |
| description | We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a neurotoxin-producing Clostridium botulinum and an acute infection with enterotoxin-producing Clostridium perfringens. |
| format | Article |
| id | doaj-art-9e166a00ad5c46a5afc73d2dba7d2a78 |
| institution | Kabale University |
| issn | 2950-5410 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Pediatrics: Clinical Practice |
| spelling | doaj-art-9e166a00ad5c46a5afc73d2dba7d2a782025-02-06T05:13:11ZengElsevierJournal of Pediatrics: Clinical Practice2950-54102025-03-0115200140Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old InfantBarbara Schaub, MD0Carolyn Luhman-Lunt, MD1Andrea Ott, MD2Maren Krüger, DSc3Martin Skiba, PhD4Sylvia Worbs, PhD5Brigitte G. Dorner, PhD6Michael Buettcher, MD7Martin B. Dorner, PhD8Pediatric Neurology Unit, Children's Hospital Lucerne, Lucerne Cantonal Hospital, Lucerne, SwitzerlandIntensive Care Unit, Children's Hospital Lucerne, Lucerne Cantonal Hospital, Lucerne, SwitzerlandGeneral Pediatric Unit, Children's Hospital Lucerne, Lucerne Cantonal Hospital, Lucerne, SwitzerlandConsultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Berlin, GermanyConsultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Berlin, GermanyConsultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Berlin, GermanyConsultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Berlin, GermanyPaediatric Infectious Diseases Unit, Children's Hospital Lucerne, Lucerne Cantonal Hospital, Lucerne, Switzerland; Paediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel, Basel, Switzerland; Faculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland; University of Basel, Basel, SwitzerlandConsultant Laboratory for Neurotoxin-Producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Berlin, Germany; Reprint requests: Martin B. Dorner, PhD, Consultant Laboratory for Neurotoxin-producing Clostridia (Botulism, Tetanus), ZBS3 – Biological Toxins, Robert Koch Institute, Seestr. 10, 13353 Berlin, Germany.We present a 5-month-old infant with a 1-day history of poor feeding and sudden progression into generalized weakness including septic shock syndrome after consumption of homemade food. Botulism and sepsis symptoms could be explained by the presence of a neurotoxin-producing Clostridium botulinum and an acute infection with enterotoxin-producing Clostridium perfringens.http://www.sciencedirect.com/science/article/pii/S295054102500002Xinfant botulismfoodborneClostridium botulinum type BClostridium perfringenstoxinotype F |
| spellingShingle | Barbara Schaub, MD Carolyn Luhman-Lunt, MD Andrea Ott, MD Maren Krüger, DSc Martin Skiba, PhD Sylvia Worbs, PhD Brigitte G. Dorner, PhD Michael Buettcher, MD Martin B. Dorner, PhD Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant Journal of Pediatrics: Clinical Practice infant botulism foodborne Clostridium botulinum type B Clostridium perfringens toxinotype F |
| title | Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant |
| title_full | Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant |
| title_fullStr | Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant |
| title_full_unstemmed | Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant |
| title_short | Conflicting Clinical Presentation of Infection with Clostridium botulinum and Clostridium perfringens in a 5-Month-Old Infant |
| title_sort | conflicting clinical presentation of infection with clostridium botulinum and clostridium perfringens in a 5 month old infant |
| topic | infant botulism foodborne Clostridium botulinum type B Clostridium perfringens toxinotype F |
| url | http://www.sciencedirect.com/science/article/pii/S295054102500002X |
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