Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide
Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2020/8894922 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560052098039808 |
|---|---|
| author | Iuliana Vaxman John Eaton Hee Eun Lee Morie A. Gertz |
| author_facet | Iuliana Vaxman John Eaton Hee Eun Lee Morie A. Gertz |
| author_sort | Iuliana Vaxman |
| collection | DOAJ |
| description | Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide. |
| format | Article |
| id | doaj-art-9e0a5969366b4c5f961b38f1ba57c15b |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-9e0a5969366b4c5f961b38f1ba57c15b2025-02-03T01:28:29ZengWileyCase Reports in Transplantation2090-69432090-69512020-01-01202010.1155/2020/88949228894922Acute Liver Rejection in a Multiple Myeloma Patient Treated with LenalidomideIuliana Vaxman0John Eaton1Hee Eun Lee2Morie A. Gertz3Division of Hematology, Mayo Clinic, Rochester, MN, USADivision of gastroenterology and hepatology, Mayo Clinic, Rochester, MN, USAPathology Department, Mayo Clinic Rochester, MN, USADivision of Hematology, Mayo Clinic, Rochester, MN, USAHerein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide.http://dx.doi.org/10.1155/2020/8894922 |
| spellingShingle | Iuliana Vaxman John Eaton Hee Eun Lee Morie A. Gertz Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide Case Reports in Transplantation |
| title | Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide |
| title_full | Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide |
| title_fullStr | Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide |
| title_full_unstemmed | Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide |
| title_short | Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide |
| title_sort | acute liver rejection in a multiple myeloma patient treated with lenalidomide |
| url | http://dx.doi.org/10.1155/2020/8894922 |
| work_keys_str_mv | AT iulianavaxman acuteliverrejectioninamultiplemyelomapatienttreatedwithlenalidomide AT johneaton acuteliverrejectioninamultiplemyelomapatienttreatedwithlenalidomide AT heeeunlee acuteliverrejectioninamultiplemyelomapatienttreatedwithlenalidomide AT morieagertz acuteliverrejectioninamultiplemyelomapatienttreatedwithlenalidomide |