Acute Liver Rejection in a Multiple Myeloma Patient Treated with Lenalidomide

Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection...

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Bibliographic Details
Main Authors: Iuliana Vaxman, John Eaton, Hee Eun Lee, Morie A. Gertz
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2020/8894922
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Summary:Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide.
ISSN:2090-6943
2090-6951