Cell-type specific effects of the long non-coding RNA HIF1A-AS3 on HIF1A expression in kidney cells

Cell-type specific effects of the long non-coding RNA HIF1A-AS3 on HIF1A expression in kidney cells

Abstract The hypoxia-inducible factor 1α (Hif1α) represents the master transcription factor coordinating cellular responses to oxygen depletion. With hundreds of target genes it plays a key role in numerous bio-medical conditions as well as neoplastic and non-cancerous diseases, which in turn requir...

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Bibliographic Details
Main Authors: Simone Reichelt-Wurm, Lena Knauss, Bettina Strasser, Mona Scharf, Kathrin Holler, Elke Eggenhofer, Markus Kretz, Bernhard Banas, Miriam C. Banas
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
HIF1A
HIF1A-AS3
HIF1A-AS2
Hypoxia
Hyperglycemia
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-025-12441-5
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