A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients
People with neuropsychiatric disorders such as schizophrenia often display deficits in spatial working memory and attention. Evaluating working memory and attention in schizophrenia patients is usually based on traditional tasks and the interviewer’s judgment. We developed a simple Spatial Working M...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2013/130642 |
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| author | Wei Song Kai Zhang Jinhua Sun Lina Ma Forrest Fabian Jesse Xiaochun Teng Ying Zhou Hechen Bao Shiqing Chen Shuai Wang Beimeng Yang Xixia Chu Wenhua Ding Yasong Du Zaohuo Cheng Bin Wu Shanguang Chen Guang He Lin He Xiaoping Chen Weidong Li |
| author_facet | Wei Song Kai Zhang Jinhua Sun Lina Ma Forrest Fabian Jesse Xiaochun Teng Ying Zhou Hechen Bao Shiqing Chen Shuai Wang Beimeng Yang Xixia Chu Wenhua Ding Yasong Du Zaohuo Cheng Bin Wu Shanguang Chen Guang He Lin He Xiaoping Chen Weidong Li |
| author_sort | Wei Song |
| collection | DOAJ |
| description | People with neuropsychiatric disorders such as schizophrenia often display deficits in spatial working memory and attention. Evaluating working memory and attention in schizophrenia patients is usually based on traditional tasks and the interviewer’s judgment. We developed a simple Spatial Working Memory and Attention Test on Paired Symbols (SWAPS). It takes only several minutes to complete, comprising 101 trials for each subject. In this study, we tested 72 schizophrenia patients and 188 healthy volunteers in China. In a healthy control group with ages ranging from 12 to 60, the efficiency score (accuracy divided by reaction time) reached a peak in the 20–27 age range and then declined with increasing age. Importantly, schizophrenia patients failed to display this developmental trend in the same age range and adults had significant deficits compared to the control group. Our data suggests that this simple Spatial Working Memory and Attention Test on Paired Symbols can be a useful tool for studies of spatial working memory and attention in neuropsychiatric disorders. |
| format | Article |
| id | doaj-art-9de15cac2d1443dbb919a04b47d9c86c |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-9de15cac2d1443dbb919a04b47d9c86c2025-02-03T05:52:19ZengWileyNeural Plasticity2090-59041687-54432013-01-01201310.1155/2013/130642130642A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia PatientsWei Song0Kai Zhang1Jinhua Sun2Lina Ma3Forrest Fabian Jesse4Xiaochun Teng5Ying Zhou6Hechen Bao7Shiqing Chen8Shuai Wang9Beimeng Yang10Xixia Chu11Wenhua Ding12Yasong Du13Zaohuo Cheng14Bin Wu15Shanguang Chen16Guang He17Lin He18Xiaoping Chen19Weidong Li20Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaWuxi Mental Health Center, Wuxi 214151, ChinaShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Endocrinology and Metabolism, The First Affliliated Hospital, China Medical University, Shenyang 110001, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, ChinaShanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, ChinaWuxi Mental Health Center, Wuxi 214151, ChinaNational Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094, ChinaNational Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaNational Key Laboratory of Human Factors Engineering, China Astronaut Research and Training Center, Beijing 100094, ChinaBio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, ChinaPeople with neuropsychiatric disorders such as schizophrenia often display deficits in spatial working memory and attention. Evaluating working memory and attention in schizophrenia patients is usually based on traditional tasks and the interviewer’s judgment. We developed a simple Spatial Working Memory and Attention Test on Paired Symbols (SWAPS). It takes only several minutes to complete, comprising 101 trials for each subject. In this study, we tested 72 schizophrenia patients and 188 healthy volunteers in China. In a healthy control group with ages ranging from 12 to 60, the efficiency score (accuracy divided by reaction time) reached a peak in the 20–27 age range and then declined with increasing age. Importantly, schizophrenia patients failed to display this developmental trend in the same age range and adults had significant deficits compared to the control group. Our data suggests that this simple Spatial Working Memory and Attention Test on Paired Symbols can be a useful tool for studies of spatial working memory and attention in neuropsychiatric disorders.http://dx.doi.org/10.1155/2013/130642 |
| spellingShingle | Wei Song Kai Zhang Jinhua Sun Lina Ma Forrest Fabian Jesse Xiaochun Teng Ying Zhou Hechen Bao Shiqing Chen Shuai Wang Beimeng Yang Xixia Chu Wenhua Ding Yasong Du Zaohuo Cheng Bin Wu Shanguang Chen Guang He Lin He Xiaoping Chen Weidong Li A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients Neural Plasticity |
| title | A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients |
| title_full | A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients |
| title_fullStr | A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients |
| title_full_unstemmed | A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients |
| title_short | A Simple Spatial Working Memory and Attention Test on Paired Symbols Shows Developmental Deficits in Schizophrenia Patients |
| title_sort | simple spatial working memory and attention test on paired symbols shows developmental deficits in schizophrenia patients |
| url | http://dx.doi.org/10.1155/2013/130642 |
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