Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
Fibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile b...
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Format: | Article |
Language: | English |
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Shiraz University of Medical Sciences
2024-12-01
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Series: | Iranian Journal of Medical Sciences |
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Online Access: | https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdf |
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author | Abbas Karimi Mahboube Hasheminasab Samira Derakhshan Dariyoush Goudarzi Pour Mahdis Khazaeli Najafabadi Razie Hosseininavaz |
author_facet | Abbas Karimi Mahboube Hasheminasab Samira Derakhshan Dariyoush Goudarzi Pour Mahdis Khazaeli Najafabadi Razie Hosseininavaz |
author_sort | Abbas Karimi |
collection | DOAJ |
description | Fibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile bone defect due to cortex thinning. This report presented a case of monostotic fibrous dysplasia of a 43-year-old woman with involvement of the right maxillary jaw and sinuses, which indicated unusual histopathological features. The patient was referred to the Department of Oral and Maxillofacial Surgery of Tehran University of Medical Sciences (Tehran, Iran) in 2022. Radiological and histological findings were discussed. The unusual histomorphic pattern of the lesion caused uncertainty and resulted in a missed definitive diagnosis in the primary biopsy. It was highlighted that awareness of rare histologic variants in fibro-osseous lesions especially fibrous dysplasia was required to improve diagnostic confidence. |
format | Article |
id | doaj-art-9dd4ff38fd3e4183b97d9416e67e087a |
institution | Kabale University |
issn | 0253-0716 1735-3688 |
language | English |
publishDate | 2024-12-01 |
publisher | Shiraz University of Medical Sciences |
record_format | Article |
series | Iranian Journal of Medical Sciences |
spelling | doaj-art-9dd4ff38fd3e4183b97d9416e67e087a2025-01-18T08:52:09ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882024-12-01491280881210.30476/ijms.2024.101751.345550559Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case ReportAbbas Karimi0Mahboube Hasheminasab1Samira Derakhshan2Dariyoush Goudarzi Pour3Mahdis Khazaeli Najafabadi4Razie Hosseininavaz5Department of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranFibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile bone defect due to cortex thinning. This report presented a case of monostotic fibrous dysplasia of a 43-year-old woman with involvement of the right maxillary jaw and sinuses, which indicated unusual histopathological features. The patient was referred to the Department of Oral and Maxillofacial Surgery of Tehran University of Medical Sciences (Tehran, Iran) in 2022. Radiological and histological findings were discussed. The unusual histomorphic pattern of the lesion caused uncertainty and resulted in a missed definitive diagnosis in the primary biopsy. It was highlighted that awareness of rare histologic variants in fibro-osseous lesions especially fibrous dysplasia was required to improve diagnostic confidence.https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdffibrous dysplasia of boneadipose tissuemetamorphosis, monostatic |
spellingShingle | Abbas Karimi Mahboube Hasheminasab Samira Derakhshan Dariyoush Goudarzi Pour Mahdis Khazaeli Najafabadi Razie Hosseininavaz Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report Iranian Journal of Medical Sciences fibrous dysplasia of bone adipose tissue metamorphosis, monostatic |
title | Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report |
title_full | Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report |
title_fullStr | Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report |
title_full_unstemmed | Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report |
title_short | Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report |
title_sort | monostotic fibrous dysplasia with rare histopathologic features a case report |
topic | fibrous dysplasia of bone adipose tissue metamorphosis, monostatic |
url | https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdf |
work_keys_str_mv | AT abbaskarimi monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport AT mahboubehasheminasab monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport AT samiraderakhshan monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport AT dariyoushgoudarzipour monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport AT mahdiskhazaelinajafabadi monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport AT raziehosseininavaz monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport |