Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report

Fibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile b...

Full description

Saved in:
Bibliographic Details
Main Authors: Abbas Karimi, Mahboube Hasheminasab, Samira Derakhshan, Dariyoush Goudarzi Pour, Mahdis Khazaeli Najafabadi, Razie Hosseininavaz
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2024-12-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832595700319256576
author Abbas Karimi
Mahboube Hasheminasab
Samira Derakhshan
Dariyoush Goudarzi Pour
Mahdis Khazaeli Najafabadi
Razie Hosseininavaz
author_facet Abbas Karimi
Mahboube Hasheminasab
Samira Derakhshan
Dariyoush Goudarzi Pour
Mahdis Khazaeli Najafabadi
Razie Hosseininavaz
author_sort Abbas Karimi
collection DOAJ
description Fibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile bone defect due to cortex thinning. This report presented a case of monostotic fibrous dysplasia of a 43-year-old woman with involvement of the right maxillary jaw and sinuses, which indicated unusual histopathological features. The patient was referred to the Department of Oral and Maxillofacial Surgery of Tehran University of Medical Sciences (Tehran, Iran) in 2022. Radiological and histological findings were discussed. The unusual histomorphic pattern of the lesion caused uncertainty and resulted in a missed definitive diagnosis in the primary biopsy. It was highlighted that awareness of rare histologic variants in fibro-osseous lesions especially fibrous dysplasia was required to improve diagnostic confidence.
format Article
id doaj-art-9dd4ff38fd3e4183b97d9416e67e087a
institution Kabale University
issn 0253-0716
1735-3688
language English
publishDate 2024-12-01
publisher Shiraz University of Medical Sciences
record_format Article
series Iranian Journal of Medical Sciences
spelling doaj-art-9dd4ff38fd3e4183b97d9416e67e087a2025-01-18T08:52:09ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882024-12-01491280881210.30476/ijms.2024.101751.345550559Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case ReportAbbas Karimi0Mahboube Hasheminasab1Samira Derakhshan2Dariyoush Goudarzi Pour3Mahdis Khazaeli Najafabadi4Razie Hosseininavaz5Department of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Surgery, Craniomaxillofacial Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, Dr. Shariati Hospital, Tehran University of Medical Sciences, Tehran, IranDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Tehran University of Medical Sciences, Tehran, IranFibrous dysplasia is a slow-progressing benign condition characterized by abnormal bone formation that leads to some skeletal disorders. Although some of the fibrous dysplasia have unusual clinical and radiographic features that can lead to a challenging diagnosis, most lesions reveal an expansile bone defect due to cortex thinning. This report presented a case of monostotic fibrous dysplasia of a 43-year-old woman with involvement of the right maxillary jaw and sinuses, which indicated unusual histopathological features. The patient was referred to the Department of Oral and Maxillofacial Surgery of Tehran University of Medical Sciences (Tehran, Iran) in 2022. Radiological and histological findings were discussed. The unusual histomorphic pattern of the lesion caused uncertainty and resulted in a missed definitive diagnosis in the primary biopsy. It was highlighted that awareness of rare histologic variants in fibro-osseous lesions especially fibrous dysplasia was required to improve diagnostic confidence.https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdffibrous dysplasia of boneadipose tissuemetamorphosis, monostatic
spellingShingle Abbas Karimi
Mahboube Hasheminasab
Samira Derakhshan
Dariyoush Goudarzi Pour
Mahdis Khazaeli Najafabadi
Razie Hosseininavaz
Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
Iranian Journal of Medical Sciences
fibrous dysplasia of bone
adipose tissue
metamorphosis, monostatic
title Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
title_full Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
title_fullStr Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
title_full_unstemmed Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
title_short Monostotic Fibrous Dysplasia with Rare Histopathologic Features: A Case Report
title_sort monostotic fibrous dysplasia with rare histopathologic features a case report
topic fibrous dysplasia of bone
adipose tissue
metamorphosis, monostatic
url https://ijms.sums.ac.ir/article_50559_dc31df0c202894731f2230eaf16218a2.pdf
work_keys_str_mv AT abbaskarimi monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport
AT mahboubehasheminasab monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport
AT samiraderakhshan monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport
AT dariyoushgoudarzipour monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport
AT mahdiskhazaelinajafabadi monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport
AT raziehosseininavaz monostoticfibrousdysplasiawithrarehistopathologicfeaturesacasereport