Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C

BACKGROUND: Treatment of chronic hepatitis C virus (HCV) infection with interferon alpha-2b and ribavirin is costly in terms of side effects, medical resources and drug costs. Furthermore, less than 50% of patients overall have a sustained virological response (SVR).

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Bibliographic Details
Main Authors: Louis WC Liu, George Tomlinson, Tony Mazzulli, Alison Murray, Jenny Heathcote
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2003/351816
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author Louis WC Liu
George Tomlinson
Tony Mazzulli
Alison Murray
Jenny Heathcote
author_facet Louis WC Liu
George Tomlinson
Tony Mazzulli
Alison Murray
Jenny Heathcote
author_sort Louis WC Liu
collection DOAJ
description BACKGROUND: Treatment of chronic hepatitis C virus (HCV) infection with interferon alpha-2b and ribavirin is costly in terms of side effects, medical resources and drug costs. Furthermore, less than 50% of patients overall have a sustained virological response (SVR).
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institution Kabale University
issn 0835-7900
language English
publishDate 2003-01-01
publisher Wiley
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series Canadian Journal of Gastroenterology
spelling doaj-art-9d8ec1150be14a4b9e2a92e675fd02192025-02-03T05:58:08ZengWileyCanadian Journal of Gastroenterology0835-79002003-01-0117848348710.1155/2003/351816Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis CLouis WC Liu0George Tomlinson1Tony Mazzulli2Alison Murray3Jenny Heathcote4Department of Medicine, McMaster University, Hamilton, Ontario, CanadaUniversity Health Network, Department of Clinical Epidemiology, CanadaToronto Medical Labs/Mount Sinai Hospital, Department of Microbiology, Toronto, Ontario, CanadaGlaxo SmithKline, Greenford, UKUniversity Health Network, Department of Medicine, Toronto, Ontario, CanadaBACKGROUND: Treatment of chronic hepatitis C virus (HCV) infection with interferon alpha-2b and ribavirin is costly in terms of side effects, medical resources and drug costs. Furthermore, less than 50% of patients overall have a sustained virological response (SVR).http://dx.doi.org/10.1155/2003/351816
spellingShingle Louis WC Liu
George Tomlinson
Tony Mazzulli
Alison Murray
Jenny Heathcote
Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
Canadian Journal of Gastroenterology
title Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
title_full Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
title_fullStr Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
title_full_unstemmed Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
title_short Early Prediction of Nonresponders to Treatment with Interferon Alpha-2B and Ribavirin in Patients with Chronic Hepatitis C
title_sort early prediction of nonresponders to treatment with interferon alpha 2b and ribavirin in patients with chronic hepatitis c
url http://dx.doi.org/10.1155/2003/351816
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