Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis
This study is aimed at providing an effective method for determining strain-load relationship and at quantifying the strain distribution within the whole tibia under axial compressive load on rats. Rat tibial models with axial compressive load were designed. Strains in three directions (0°, 45°, and...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
|
| Series: | Applied Bionics and Biomechanics |
| Online Access: | http://dx.doi.org/10.1155/2019/1736763 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558881589428224 |
|---|---|
| author | Jiazi Gao Bei Liu Min Zhang He Gong Bingzhao Gao |
| author_facet | Jiazi Gao Bei Liu Min Zhang He Gong Bingzhao Gao |
| author_sort | Jiazi Gao |
| collection | DOAJ |
| description | This study is aimed at providing an effective method for determining strain-load relationship and at quantifying the strain distribution within the whole tibia under axial compressive load on rats. Rat tibial models with axial compressive load were designed. Strains in three directions (0°, 45°, and 90°) at the proximal shaft of the tibia were measured by using a strain gauge rosette, which was used to calculate the maximum and minimum principal strains. Moreover, the strain at the midshaft of the tibia was measured by a single-element strain gauge. The slopes of the strain-load curves with different peak loads were calculated to assess the stability of the strain gauge measurement. Mechanical environment in the whole tibia by the axial compressive load was quantified using finite element analysis (FEA) based on microcomputed tomography images. The von Mises elastic strain distributions of the whole tibiae were evaluated. Slopes of the strain-load curves showed no significant differences among different peak loads (ANOVA; P>0.05), indicating that the strain-load relationship obtained from the strain gauge measurement was reasonable and stable. The FEA results corresponded to the experimental results with an error smaller than 15% (paired Student’s t-test, P>0.05), signifying that the FEA can simulate the experiment reasonably. FEA results showed that the von Mises elastic strain was the lowest in the middle and gradually increased to both sides along the lateral direction, with the maximal von Mises elastic strain being observed on the posterior side under the distal tibiofibular synostosis. The method of strain gauge measurements and FEA used in this study can provide a feasible way to obtain the mechanical environment of the tibiae under axial compressive load on the rats and serve as a reference for further exploring the mechanical response of the bone by axial compressive load. |
| format | Article |
| id | doaj-art-9d825d8ee0804a83bdc18332d01ea776 |
| institution | Kabale University |
| issn | 1176-2322 1754-2103 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Applied Bionics and Biomechanics |
| spelling | doaj-art-9d825d8ee0804a83bdc18332d01ea7762025-02-03T01:31:19ZengWileyApplied Bionics and Biomechanics1176-23221754-21032019-01-01201910.1155/2019/17367631736763Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element AnalysisJiazi Gao0Bei Liu1Min Zhang2He Gong3Bingzhao Gao4State Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun, ChinaDepartment of Engineering Mechanics, Nanling Campus, Jilin University, Changchun, ChinaDepartment of Engineering Mechanics, Nanling Campus, Jilin University, Changchun, ChinaState Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun, ChinaState Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun, ChinaThis study is aimed at providing an effective method for determining strain-load relationship and at quantifying the strain distribution within the whole tibia under axial compressive load on rats. Rat tibial models with axial compressive load were designed. Strains in three directions (0°, 45°, and 90°) at the proximal shaft of the tibia were measured by using a strain gauge rosette, which was used to calculate the maximum and minimum principal strains. Moreover, the strain at the midshaft of the tibia was measured by a single-element strain gauge. The slopes of the strain-load curves with different peak loads were calculated to assess the stability of the strain gauge measurement. Mechanical environment in the whole tibia by the axial compressive load was quantified using finite element analysis (FEA) based on microcomputed tomography images. The von Mises elastic strain distributions of the whole tibiae were evaluated. Slopes of the strain-load curves showed no significant differences among different peak loads (ANOVA; P>0.05), indicating that the strain-load relationship obtained from the strain gauge measurement was reasonable and stable. The FEA results corresponded to the experimental results with an error smaller than 15% (paired Student’s t-test, P>0.05), signifying that the FEA can simulate the experiment reasonably. FEA results showed that the von Mises elastic strain was the lowest in the middle and gradually increased to both sides along the lateral direction, with the maximal von Mises elastic strain being observed on the posterior side under the distal tibiofibular synostosis. The method of strain gauge measurements and FEA used in this study can provide a feasible way to obtain the mechanical environment of the tibiae under axial compressive load on the rats and serve as a reference for further exploring the mechanical response of the bone by axial compressive load.http://dx.doi.org/10.1155/2019/1736763 |
| spellingShingle | Jiazi Gao Bei Liu Min Zhang He Gong Bingzhao Gao Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis Applied Bionics and Biomechanics |
| title | Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis |
| title_full | Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis |
| title_fullStr | Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis |
| title_full_unstemmed | Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis |
| title_short | Strain Distribution Evaluation of Rat Tibia under Axial Compressive Load by Combining Strain Gauge Measurement and Finite Element Analysis |
| title_sort | strain distribution evaluation of rat tibia under axial compressive load by combining strain gauge measurement and finite element analysis |
| url | http://dx.doi.org/10.1155/2019/1736763 |
| work_keys_str_mv | AT jiazigao straindistributionevaluationofrattibiaunderaxialcompressiveloadbycombiningstraingaugemeasurementandfiniteelementanalysis AT beiliu straindistributionevaluationofrattibiaunderaxialcompressiveloadbycombiningstraingaugemeasurementandfiniteelementanalysis AT minzhang straindistributionevaluationofrattibiaunderaxialcompressiveloadbycombiningstraingaugemeasurementandfiniteelementanalysis AT hegong straindistributionevaluationofrattibiaunderaxialcompressiveloadbycombiningstraingaugemeasurementandfiniteelementanalysis AT bingzhaogao straindistributionevaluationofrattibiaunderaxialcompressiveloadbycombiningstraingaugemeasurementandfiniteelementanalysis |