Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report
Introduction. Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatism types in elderly population. The link between cancer and PMR is a matter of debate. Methods. We report two cases of PMR leading to the diagnosis of lymphoma and the growing interest of PET-TDM in this indica...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2016/2986297 |
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| author | Frank Verhoeven Xavier Guillot Mickaël Chouk Clément Prati Daniel Wendling |
| author_facet | Frank Verhoeven Xavier Guillot Mickaël Chouk Clément Prati Daniel Wendling |
| author_sort | Frank Verhoeven |
| collection | DOAJ |
| description | Introduction. Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatism types in elderly population. The link between cancer and PMR is a matter of debate. Methods. We report two cases of PMR leading to the diagnosis of lymphoma and the growing interest of PET-TDM in this indication. Results. A 84-year-old man known for idiopathic neutropenia presented an inflammatory arthromyalgia of the limb girdle since one month. Blood exams highlighted the presence of a monoclonal B cell clone. Bone marrow concluded to a B cell lymphoma of the marginal zone. He was successfully treated with 0.3 mg/kg/d of prednisone, and response was sustained after 6 months. A 73-year-old man known for prostatic neoplasia in remission for 5 years presented arthromyalgia of the limb girdle since one month. PET-CT revealed bursitis of the hips and the shoulders, no prostatic cancer recurrence, and a metabolically active iliac lymphadenopathy whose pathologic exam concluded to a low grade follicular lymphoma. He was successfully treated with 0.3 mg/kg/d of prednisone. Conclusion. These observations may imply that lymphoma is sometimes already present when PMR is diagnosed and PET-CT is a useful tool in the initial assessment of PMR to avoid missing neoplasia. |
| format | Article |
| id | doaj-art-9d76064bd20c4759a9296c8224b21bb4 |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-9d76064bd20c4759a9296c8224b21bb42025-02-03T06:07:03ZengWileyCase Reports in Rheumatology2090-68892090-68972016-01-01201610.1155/2016/29862972986297Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case ReportFrank Verhoeven0Xavier Guillot1Mickaël Chouk2Clément Prati3Daniel Wendling4Department of Rheumatology, CHRU Besançon, 2 Boulevard Fleming, 25030 Besançon, FranceDepartment of Rheumatology, CHRU Besançon, 2 Boulevard Fleming, 25030 Besançon, FranceDepartment of Rheumatology, CHRU Besançon, 2 Boulevard Fleming, 25030 Besançon, FranceDepartment of Rheumatology, CHRU Besançon, 2 Boulevard Fleming, 25030 Besançon, FranceDepartment of Rheumatology, CHRU Besançon, 2 Boulevard Fleming, 25030 Besançon, FranceIntroduction. Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatism types in elderly population. The link between cancer and PMR is a matter of debate. Methods. We report two cases of PMR leading to the diagnosis of lymphoma and the growing interest of PET-TDM in this indication. Results. A 84-year-old man known for idiopathic neutropenia presented an inflammatory arthromyalgia of the limb girdle since one month. Blood exams highlighted the presence of a monoclonal B cell clone. Bone marrow concluded to a B cell lymphoma of the marginal zone. He was successfully treated with 0.3 mg/kg/d of prednisone, and response was sustained after 6 months. A 73-year-old man known for prostatic neoplasia in remission for 5 years presented arthromyalgia of the limb girdle since one month. PET-CT revealed bursitis of the hips and the shoulders, no prostatic cancer recurrence, and a metabolically active iliac lymphadenopathy whose pathologic exam concluded to a low grade follicular lymphoma. He was successfully treated with 0.3 mg/kg/d of prednisone. Conclusion. These observations may imply that lymphoma is sometimes already present when PMR is diagnosed and PET-CT is a useful tool in the initial assessment of PMR to avoid missing neoplasia.http://dx.doi.org/10.1155/2016/2986297 |
| spellingShingle | Frank Verhoeven Xavier Guillot Mickaël Chouk Clément Prati Daniel Wendling Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report Case Reports in Rheumatology |
| title | Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report |
| title_full | Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report |
| title_fullStr | Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report |
| title_full_unstemmed | Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report |
| title_short | Polymyalgia Rheumatica Revealing a Lymphoma: A Two-Case Report |
| title_sort | polymyalgia rheumatica revealing a lymphoma a two case report |
| url | http://dx.doi.org/10.1155/2016/2986297 |
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