Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging

Phase analysis has been validated to measure left ventricular (LV) dyssynchrony from resting gated SPECT myocardial perfusion imaging (MPI). In 1-day rest/stress protocols, often only post-stress gated data are acquired. The purpose of this study was to determine whether LV dyssynchrony parameters m...

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Main Authors: Yanli Zhou, Dianfu Li, Jianlin Feng, Donglan Yuan, Zenic Patel, Kejiang Cao, Ji Chen
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2013-01-01
Series:World Journal of Nuclear Medicine
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Online Access:http://www.wjnm.org/article.asp?issn=1450-1147;year=2013;volume=12;issue=1;spage=3;epage=7;aulast=Zhou
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author Yanli Zhou
Dianfu Li
Jianlin Feng
Donglan Yuan
Zenic Patel
Kejiang Cao
Ji Chen
author_facet Yanli Zhou
Dianfu Li
Jianlin Feng
Donglan Yuan
Zenic Patel
Kejiang Cao
Ji Chen
author_sort Yanli Zhou
collection DOAJ
description Phase analysis has been validated to measure left ventricular (LV) dyssynchrony from resting gated SPECT myocardial perfusion imaging (MPI). In 1-day rest/stress protocols, often only post-stress gated data are acquired. The purpose of this study was to determine whether LV dyssynchrony parameters measured at post-stress significantly differ from those measured at rest. Sixty normal subjects, 40 patients with stress-induced ischemia but normal LV function, and 29 patients with LV dysfunction were included in this study. All patients were scanned using a 2-day Technetium-99m sestamibi (MIBI) MPI protocol, where gated SPECT data were acquired at 60 min post injection of the radiotracer. LV dyssynchrony parameters at post-stress and at rest were calculated and compared using paired t-test. There were no significant differences in the LV dyssynchrony parameters between post-stress and resting in all cohorts. No patient showed differences in the LV dyssynchrony parameters between the post-stress and resting scans significantly greater than the reported variations in these parameters between serial resting scans. There was no significant difference in dyssynchrony parameters measured at rest and 60 min after stress on MPI gated images.
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spelling doaj-art-9d6f28fc874e4ccf9bbac0a0d37a2ef02025-08-20T02:54:44ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11472013-01-011213710.4103/1450-1147.113931Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion ImagingYanli ZhouDianfu LiJianlin FengDonglan YuanZenic PatelKejiang CaoJi ChenPhase analysis has been validated to measure left ventricular (LV) dyssynchrony from resting gated SPECT myocardial perfusion imaging (MPI). In 1-day rest/stress protocols, often only post-stress gated data are acquired. The purpose of this study was to determine whether LV dyssynchrony parameters measured at post-stress significantly differ from those measured at rest. Sixty normal subjects, 40 patients with stress-induced ischemia but normal LV function, and 29 patients with LV dysfunction were included in this study. All patients were scanned using a 2-day Technetium-99m sestamibi (MIBI) MPI protocol, where gated SPECT data were acquired at 60 min post injection of the radiotracer. LV dyssynchrony parameters at post-stress and at rest were calculated and compared using paired t-test. There were no significant differences in the LV dyssynchrony parameters between post-stress and resting in all cohorts. No patient showed differences in the LV dyssynchrony parameters between the post-stress and resting scans significantly greater than the reported variations in these parameters between serial resting scans. There was no significant difference in dyssynchrony parameters measured at rest and 60 min after stress on MPI gated images.http://www.wjnm.org/article.asp?issn=1450-1147;year=2013;volume=12;issue=1;spage=3;epage=7;aulast=ZhouLeft ventricular dyssynchronymyocardial perfusion imagingphase analysis
spellingShingle Yanli Zhou
Dianfu Li
Jianlin Feng
Donglan Yuan
Zenic Patel
Kejiang Cao
Ji Chen
Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
World Journal of Nuclear Medicine
Left ventricular dyssynchrony
myocardial perfusion imaging
phase analysis
title Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
title_full Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
title_fullStr Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
title_full_unstemmed Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
title_short Left Ventricular Dyssynchrony Parameters Measured by Phase Analysis of Post-stress and Resting Gated SPECT Myocardial Perfusion Imaging
title_sort left ventricular dyssynchrony parameters measured by phase analysis of post stress and resting gated spect myocardial perfusion imaging
topic Left ventricular dyssynchrony
myocardial perfusion imaging
phase analysis
url http://www.wjnm.org/article.asp?issn=1450-1147;year=2013;volume=12;issue=1;spage=3;epage=7;aulast=Zhou
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