Predictive factors and nomogram for the risk of cytokine release syndrome with anti-CD3 × CD20 bispecific antibodies for Chinese patients

Predictive factors and nomogram for the risk of cytokine release syndrome with anti-CD3 × CD20 bispecific antibodies for Chinese patients

Abstract Background Targeting CD3 × CD20 bispecific antibodies (BsAbs) represents a new milestone in the salvage therapy of relapsed/relapsed large B cell lymphoma and follicular lymphoma. However, cytokine release syndrome (CRS) remains one of the major concerns in clinical practice of CD3 × CD20 B...

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Main Authors: Peng Sun, Cui Chen, Bai-Tian Zhao, Bo-Yan Zhang, Hang Yang, Yu Wang, Fei Xu, Kang-Ming Huang, Yin-Ting Liu, Mei-Shuo Ouyang, Jia-Jia Huang, Pan-Pan Liu, Ying Guo, Zhi-Ming Li
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Cancer Immunology, Immunotherapy
Subjects:
CD3 × CD20 bispecific antibodies (BsAbs)
Cytokine release syndrome (CRS)
Predictive factors
Nomogram
Online Access:https://doi.org/10.1007/s00262-025-04080-6
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https://doi.org/10.1007/s00262-025-04080-6

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