Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada
In 1992, a surveillance study was performed in Canada to determine the susceptibility of nosocomial Gram-negative rods to several wide spectrum antimicrobials. Consecutive isolates from 10 institutions, as well as additional strains of selected species of Enterobacteriaceae that are known to possess...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
1995-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1995/297910 |
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| _version_ | 1832545938171756544 |
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| author | Shelley R Scriver Canadian Antimicrobial Resistance Study Group Donald E Low |
| author_facet | Shelley R Scriver Canadian Antimicrobial Resistance Study Group Donald E Low |
| author_sort | Shelley R Scriver |
| collection | DOAJ |
| description | In 1992, a surveillance study was performed in Canada to determine the susceptibility of nosocomial Gram-negative rods to several wide spectrum antimicrobials. Consecutive isolates from 10 institutions, as well as additional strains of selected species of Enterobacteriaceae that are known to possess the Bush group 1 beta-lactamase, were tested for susceptibility to 12 antimicrobials. Third-generation cephalosporin resistance was found to be as high as 29% in Enterobacter cloacae that possesses the Bush group 1 beta-lactamase and less than 4% in those isolates not possessing this enzyme. Cefepime equalled or exceeded the activity of the third-generation cephalosporins against the species of Enterobacteriaceae that demonstrated resistance to the third-generation cephalosporins. |
| format | Article |
| id | doaj-art-9d2945c9aff74ff5a9de64cd26865117 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1995-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-9d2945c9aff74ff5a9de64cd268651172025-02-03T07:24:17ZengWileyCanadian Journal of Infectious Diseases1180-23321995-01-0162768210.1155/1995/297910Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across CanadaShelley R ScriverCanadian Antimicrobial Resistance Study GroupDonald E LowIn 1992, a surveillance study was performed in Canada to determine the susceptibility of nosocomial Gram-negative rods to several wide spectrum antimicrobials. Consecutive isolates from 10 institutions, as well as additional strains of selected species of Enterobacteriaceae that are known to possess the Bush group 1 beta-lactamase, were tested for susceptibility to 12 antimicrobials. Third-generation cephalosporin resistance was found to be as high as 29% in Enterobacter cloacae that possesses the Bush group 1 beta-lactamase and less than 4% in those isolates not possessing this enzyme. Cefepime equalled or exceeded the activity of the third-generation cephalosporins against the species of Enterobacteriaceae that demonstrated resistance to the third-generation cephalosporins.http://dx.doi.org/10.1155/1995/297910 |
| spellingShingle | Shelley R Scriver Canadian Antimicrobial Resistance Study Group Donald E Low Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada Canadian Journal of Infectious Diseases |
| title | Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada |
| title_full | Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada |
| title_fullStr | Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada |
| title_full_unstemmed | Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada |
| title_short | Comparative Activity of Several Antimicrobial Agents against Nosocomial Gram-Negative Rods Isolated across Canada |
| title_sort | comparative activity of several antimicrobial agents against nosocomial gram negative rods isolated across canada |
| url | http://dx.doi.org/10.1155/1995/297910 |
| work_keys_str_mv | AT shelleyrscriver comparativeactivityofseveralantimicrobialagentsagainstnosocomialgramnegativerodsisolatedacrosscanada AT canadianantimicrobialresistancestudygroup comparativeactivityofseveralantimicrobialagentsagainstnosocomialgramnegativerodsisolatedacrosscanada AT donaldelow comparativeactivityofseveralantimicrobialagentsagainstnosocomialgramnegativerodsisolatedacrosscanada |