Development of Accurate Long-lead COVID-19 Forecast.

Coronavirus disease 2019 (COVID-19) will likely remain a major public health burden; accurate forecast of COVID-19 epidemic outcomes several months into the future is needed to support more proactive planning. Here, we propose strategies to address three major forecast challenges, i.e., error growth...

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Main Authors: Wan Yang, Jeffrey Shaman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-07-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011278&type=printable
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author Wan Yang
Jeffrey Shaman
author_facet Wan Yang
Jeffrey Shaman
author_sort Wan Yang
collection DOAJ
description Coronavirus disease 2019 (COVID-19) will likely remain a major public health burden; accurate forecast of COVID-19 epidemic outcomes several months into the future is needed to support more proactive planning. Here, we propose strategies to address three major forecast challenges, i.e., error growth, the emergence of new variants, and infection seasonality. Using these strategies in combination we generate retrospective predictions of COVID-19 cases and deaths 6 months in the future for 10 representative US states. Tallied over >25,000 retrospective predictions through September 2022, the forecast approach using all three strategies consistently outperformed a baseline forecast approach without these strategies across different variant waves and locations, for all forecast targets. Overall, probabilistic forecast accuracy improved by 64% and 38% and point prediction accuracy by 133% and 87% for cases and deaths, respectively. Real-time 6-month lead predictions made in early October 2022 suggested large attack rates in most states but a lower burden of deaths than previous waves during October 2022 -March 2023; these predictions are in general accurate compared to reported data. The superior skill of the forecast methods developed here demonstrate means for generating more accurate long-lead forecast of COVID-19 and possibly other infectious diseases.
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institution Kabale University
issn 1553-734X
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spelling doaj-art-9d154ae0d6f94820b51b4bd3b0ec842f2025-08-20T03:44:45ZengPublic Library of Science (PLoS)PLoS Computational Biology1553-734X1553-73582023-07-01197e101127810.1371/journal.pcbi.1011278Development of Accurate Long-lead COVID-19 Forecast.Wan YangJeffrey ShamanCoronavirus disease 2019 (COVID-19) will likely remain a major public health burden; accurate forecast of COVID-19 epidemic outcomes several months into the future is needed to support more proactive planning. Here, we propose strategies to address three major forecast challenges, i.e., error growth, the emergence of new variants, and infection seasonality. Using these strategies in combination we generate retrospective predictions of COVID-19 cases and deaths 6 months in the future for 10 representative US states. Tallied over >25,000 retrospective predictions through September 2022, the forecast approach using all three strategies consistently outperformed a baseline forecast approach without these strategies across different variant waves and locations, for all forecast targets. Overall, probabilistic forecast accuracy improved by 64% and 38% and point prediction accuracy by 133% and 87% for cases and deaths, respectively. Real-time 6-month lead predictions made in early October 2022 suggested large attack rates in most states but a lower burden of deaths than previous waves during October 2022 -March 2023; these predictions are in general accurate compared to reported data. The superior skill of the forecast methods developed here demonstrate means for generating more accurate long-lead forecast of COVID-19 and possibly other infectious diseases.https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011278&type=printable
spellingShingle Wan Yang
Jeffrey Shaman
Development of Accurate Long-lead COVID-19 Forecast.
PLoS Computational Biology
title Development of Accurate Long-lead COVID-19 Forecast.
title_full Development of Accurate Long-lead COVID-19 Forecast.
title_fullStr Development of Accurate Long-lead COVID-19 Forecast.
title_full_unstemmed Development of Accurate Long-lead COVID-19 Forecast.
title_short Development of Accurate Long-lead COVID-19 Forecast.
title_sort development of accurate long lead covid 19 forecast
url https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1011278&type=printable
work_keys_str_mv AT wanyang developmentofaccuratelongleadcovid19forecast
AT jeffreyshaman developmentofaccuratelongleadcovid19forecast