Investigation of the role of GEM in systemic lupus erythematosus through multi-omics joint analysis

Investigation of the role of GEM in systemic lupus erythematosus through multi-omics joint analysis

BackgroundSystemic lupus erythematosus (SLE) is a persistent autoimmune disorder marked by dysregulation of the immune system, resulting in extensive tissue inflammation and subsequent damage. Fibroblasts are essential contributors to the pathogenesis of SLE, particularly in driving the progression...

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Bibliographic Details
Main Authors: Ruofei Chen, Xiao Zhang, Yifang Shang, Huaixuan Zhang, Xiaolei Li, Hanren Dai, Zongwen Shuai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
SLE
GEM
fibroblast
immunology
therapeutic target
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1569605/full
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