Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis

Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis

Introduction The main alkaloid component in cigarettes is nicotine. Cotinine, a metabolite of nicotine, is capable of causing dependence effects through endless mechanisms modulated by the ion channel nicotinic acetylcholine receptors nAChRs. Nicotine and cotinine can also cause damage to blood vess...

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Main Authors: Kumboyono Kumboyono, Indah N. Chomsy, Nadya N. Shalshabilla, Hidayat Sujuti, Arie Srihardyastutie, Cholid T. Tjahjono, Teuku Heriansyah, Titin A. Wihastuti
Format: Article
Language:English
Published: European Publishing 2024-01-01
Series:Tobacco Induced Diseases
Subjects:
nicotine
cotinine
vascular inflammation
oxidative stress
tobacco-induced disease
Online Access:https://www.tobaccoinduceddiseases.org/Nicotine-is-associated-with-smoking-dependence-and-vascular-ninflammation-through,171356,0,2.html
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