Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease

Systematic review and bayesian network meta-analysis: comparative efficacy and safety of six commonly used biologic therapies for moderate-to-severe Crohn’s disease

BackgroundIn contrast to previous network meta-analysis using classical frequentist methods, we evaluated the efficacy and safety of six frequently-used biologics through a Bayesian method.MethodsWeb of Science, Scopus, CENTRAL, ClinicalTrials.gov and ICTRP were searched to collect randomized contro...

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Bibliographic Details
Main Authors: Haohang Su, Shengwei Xiao, Zhiqing Liang, Tianrong Xun, Jinfang Zhang, Xixiao Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
bayesian network meta-analysis
Crohn’s disease
biologic agents
efficacy
safety
GRADE
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1475222/full
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