Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview

We describe two HIV-infected patients with tuberculosis-associated immune reconstruction inflammatory syndrome (TB-IRIS): one with “paradoxical” IRIS and the other with “unmasking” IRIS. TB-IRIS in HIV-infected subjects is an exacerbation of the symptoms, signs, or radiological manifestations of a p...

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Main Authors: Klaudija Viskovic, Josip Begovac
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2013/323208
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author Klaudija Viskovic
Josip Begovac
author_facet Klaudija Viskovic
Josip Begovac
author_sort Klaudija Viskovic
collection DOAJ
description We describe two HIV-infected patients with tuberculosis-associated immune reconstruction inflammatory syndrome (TB-IRIS): one with “paradoxical” IRIS and the other with “unmasking” IRIS. TB-IRIS in HIV-infected subjects is an exacerbation of the symptoms, signs, or radiological manifestations of a pathogenic antigen, related to recovery of the immune system after immunosuppression. We focused on the radiological characteristics of TB-IRIS and the briefly literature review on this syndrome.
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institution Kabale University
issn 2090-6625
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publishDate 2013-01-01
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series Case Reports in Infectious Diseases
spelling doaj-art-9cf6b72aaf06497ab6393b02741863b62025-02-03T00:59:54ZengWileyCase Reports in Infectious Diseases2090-66252090-66332013-01-01201310.1155/2013/323208323208Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature OverviewKlaudija Viskovic0Josip Begovac1Department of Radiology and Ultrasound, University Hospital for Infectious Diseases, Mirogojska Cesta 8, 10000 Zagreb, CroatiaCenter for HIV/AIDS Infection, University Hospital for Infectious Diseases and School of Medicine, University of Zagreb, CroatiaWe describe two HIV-infected patients with tuberculosis-associated immune reconstruction inflammatory syndrome (TB-IRIS): one with “paradoxical” IRIS and the other with “unmasking” IRIS. TB-IRIS in HIV-infected subjects is an exacerbation of the symptoms, signs, or radiological manifestations of a pathogenic antigen, related to recovery of the immune system after immunosuppression. We focused on the radiological characteristics of TB-IRIS and the briefly literature review on this syndrome.http://dx.doi.org/10.1155/2013/323208
spellingShingle Klaudija Viskovic
Josip Begovac
Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
Case Reports in Infectious Diseases
title Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
title_full Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
title_fullStr Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
title_full_unstemmed Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
title_short Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview
title_sort tuberculosis associated immune reconstruction inflammatory syndrome tb iris in hiv infected patients report of two cases and the literature overview
url http://dx.doi.org/10.1155/2013/323208
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