Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors

Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors

Objective: To assess the protective effects of trigonelline against spinal cord injury (SCI) in rats. Methods: Rats (Sprague-Dawley, male) were randomly assigned to seven groups (n=15 per group): normal, sham, SCI control (1% DMSO), methylprednisolone (30 mg/kg), and trigonelline (50, 100, and 200 m...

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Bibliographic Details
Main Authors: Zhi-Lan Ye, Yuan Cao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
bax
bcl-2
bdnf
cox-ii
spinal cord injury
trigonelline
Online Access:https://journals.lww.com/10.4103/apjtb.apjtb_519_24
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