Current treatment strategy for resectable scalp and neck melanoma

Melanoma is a malignant skin tumor associated with a poor clinical prognosis. The incidence of melanoma is constantly rising. Several studies demonstrated that overall and relapse-free survival rates in patients with head and neck melanoma were lower than those in patients with skin melanoma of othe...

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Main Authors: A. P. Polyakov, I. V. Rebrikova, A. V. Mordovskiy
Format: Article
Language:Russian
Published: ABV-press 2021-08-01
Series:Опухоли головы и шеи
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Online Access:https://ogsh.abvpress.ru/jour/article/view/647
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author A. P. Polyakov
I. V. Rebrikova
A. V. Mordovskiy
author_facet A. P. Polyakov
I. V. Rebrikova
A. V. Mordovskiy
author_sort A. P. Polyakov
collection DOAJ
description Melanoma is a malignant skin tumor associated with a poor clinical prognosis. The incidence of melanoma is constantly rising. Several studies demonstrated that overall and relapse-free survival rates in patients with head and neck melanoma were lower than those in patients with skin melanoma of other locations. Some authors showed that patients with scalp melanoma had the worst prognosis.Surgery is currently the main treatment option for resectable skin melanoma. It has a number of specific characteristics, such as the need for a smaller resection margin at primary tumor removal in some cases, lower accuracy of sentinel lymph node identification due to the complexity of lymph flow from the scalp and neck, and changes in the standard volumes of lymphadenectomy considering lymph flow from the scalp and neck. Oncologists should have reconstructive surgery skills, because their aim is not only to ensure complete tumor excision, but also to achieve a satisfactory appearance of the patient, especially if the tumor is located in the face, open areas of the head and neck and ears, since this is of functional and aesthetic importance. The administration of adjuvant therapy still causes some controversy in cases where both radiation therapy and pharmacotherapy are indicated.In this article, we describe the main characteristics of the current treatment strategy for resectable scalp and neck melanoma and cover the main problems in this area that have not been addressed so far.
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institution Kabale University
issn 2222-1468
2411-4634
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publishDate 2021-08-01
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series Опухоли головы и шеи
spelling doaj-art-9cd1663f38af478ca30012af26ea66f32025-08-20T03:37:09ZrusABV-pressОпухоли головы и шеи2222-14682411-46342021-08-01112505610.17650/2222-1468-2021-11-2-50-56446Current treatment strategy for resectable scalp and neck melanomaA. P. Polyakov0I. V. Rebrikova1A. V. Mordovskiy2P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of Russia; Peoples’ Friendship University of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaP.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of Russia; Peoples’ Friendship University of RussiaP.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of RussiaMelanoma is a malignant skin tumor associated with a poor clinical prognosis. The incidence of melanoma is constantly rising. Several studies demonstrated that overall and relapse-free survival rates in patients with head and neck melanoma were lower than those in patients with skin melanoma of other locations. Some authors showed that patients with scalp melanoma had the worst prognosis.Surgery is currently the main treatment option for resectable skin melanoma. It has a number of specific characteristics, such as the need for a smaller resection margin at primary tumor removal in some cases, lower accuracy of sentinel lymph node identification due to the complexity of lymph flow from the scalp and neck, and changes in the standard volumes of lymphadenectomy considering lymph flow from the scalp and neck. Oncologists should have reconstructive surgery skills, because their aim is not only to ensure complete tumor excision, but also to achieve a satisfactory appearance of the patient, especially if the tumor is located in the face, open areas of the head and neck and ears, since this is of functional and aesthetic importance. The administration of adjuvant therapy still causes some controversy in cases where both radiation therapy and pharmacotherapy are indicated.In this article, we describe the main characteristics of the current treatment strategy for resectable scalp and neck melanoma and cover the main problems in this area that have not been addressed so far.https://ogsh.abvpress.ru/jour/article/view/647head and neck melanomascalp melanomasentinel lymph node biopsylymphadenectomyadjuvant therapy
spellingShingle A. P. Polyakov
I. V. Rebrikova
A. V. Mordovskiy
Current treatment strategy for resectable scalp and neck melanoma
Опухоли головы и шеи
head and neck melanoma
scalp melanoma
sentinel lymph node biopsy
lymphadenectomy
adjuvant therapy
title Current treatment strategy for resectable scalp and neck melanoma
title_full Current treatment strategy for resectable scalp and neck melanoma
title_fullStr Current treatment strategy for resectable scalp and neck melanoma
title_full_unstemmed Current treatment strategy for resectable scalp and neck melanoma
title_short Current treatment strategy for resectable scalp and neck melanoma
title_sort current treatment strategy for resectable scalp and neck melanoma
topic head and neck melanoma
scalp melanoma
sentinel lymph node biopsy
lymphadenectomy
adjuvant therapy
url https://ogsh.abvpress.ru/jour/article/view/647
work_keys_str_mv AT appolyakov currenttreatmentstrategyforresectablescalpandneckmelanoma
AT ivrebrikova currenttreatmentstrategyforresectablescalpandneckmelanoma
AT avmordovskiy currenttreatmentstrategyforresectablescalpandneckmelanoma