Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

Bioinformatics-based prognostic value and in vitro functional validation of PTK6 in cutaneous melanoma

BackgroundCutaneous melanoma (CM) is a highly malignant tumor originating from melanocytes. Rising incidence rates pose a significant burden on global health and economy. Advanced CM patients face poor prognosis due to high recurrence and treatment resistance. Identifying new prognostic biomarkers a...

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Bibliographic Details
Main Authors: Yanyan Niu, Xiaoyu Liu, Aixiu Shi, Danli Tang, Xiaodong Yao, Yan Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
protein tyrosine kinase 6 (PTK6)
cutaneous melanoma (CM)
prognostic biomarker
proliferation
invasion
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1555302/full
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