Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review

Cervical cancer remains a significant global health concern, characterized by high morbidity and mortality rates. High-dose-rate brachytherapy (HDR-BT) is a critical component of cervical cancer treatment, requiring precise and efficient treatment planning. However, the process is labor-intensive, h...

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Main Authors: Junyue Shi, Jun Chen, Gaokui He, Qinghe Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1507592/full
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author Junyue Shi
Junyue Shi
Jun Chen
Gaokui He
Qinghe Peng
author_facet Junyue Shi
Junyue Shi
Jun Chen
Gaokui He
Qinghe Peng
author_sort Junyue Shi
collection DOAJ
description Cervical cancer remains a significant global health concern, characterized by high morbidity and mortality rates. High-dose-rate brachytherapy (HDR-BT) is a critical component of cervical cancer treatment, requiring precise and efficient treatment planning. However, the process is labor-intensive, heavily reliant on operator expertise, and prone to variability due to factors such as applicator shifts and organ filling changes. Recent advancements in artificial intelligence (AI), particularly in medical image processing, offer significant potential for automating and standardizing treatment planning in HDR-BT. This review examines the progress and challenge of AI applications in HDR-BT treatment planning, focusing on automatic segmentation, applicator reconstruction, dose calculation, and plan optimization. By addressing current limitations and exploring future directions, this paper aims to guide the integration of AI into clinical practice, ultimately improving treatment accuracy, reducing preparation time, and enhancing patient outcomes.
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publisher Frontiers Media S.A.
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spelling doaj-art-9ca8c5185a364d309ad8b19e042223cd2025-01-27T06:40:15ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011510.3389/fonc.2025.15075921507592Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a reviewJunyue Shi0Junyue Shi1Jun Chen2Gaokui He3Qinghe Peng4Department of Nuclear Technology Application, China Institute of Atomic Energy, Beijing, ChinaDepartment of Radiation Oncology, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, ChinaDepartment of Radiation Oncology, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, ChinaDepartment of Nuclear Technology Application, China Institute of Atomic Energy, Beijing, ChinaDepartment of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, ChinaCervical cancer remains a significant global health concern, characterized by high morbidity and mortality rates. High-dose-rate brachytherapy (HDR-BT) is a critical component of cervical cancer treatment, requiring precise and efficient treatment planning. However, the process is labor-intensive, heavily reliant on operator expertise, and prone to variability due to factors such as applicator shifts and organ filling changes. Recent advancements in artificial intelligence (AI), particularly in medical image processing, offer significant potential for automating and standardizing treatment planning in HDR-BT. This review examines the progress and challenge of AI applications in HDR-BT treatment planning, focusing on automatic segmentation, applicator reconstruction, dose calculation, and plan optimization. By addressing current limitations and exploring future directions, this paper aims to guide the integration of AI into clinical practice, ultimately improving treatment accuracy, reducing preparation time, and enhancing patient outcomes.https://www.frontiersin.org/articles/10.3389/fonc.2025.1507592/fullartificial intelligence (AI)cervical cancerhigh-dose-rate brachytherapy (HDR-BT)treatment planningdeep learning (DL)
spellingShingle Junyue Shi
Junyue Shi
Jun Chen
Gaokui He
Qinghe Peng
Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
Frontiers in Oncology
artificial intelligence (AI)
cervical cancer
high-dose-rate brachytherapy (HDR-BT)
treatment planning
deep learning (DL)
title Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
title_full Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
title_fullStr Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
title_full_unstemmed Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
title_short Artificial intelligence in high-dose-rate brachytherapy treatment planning for cervical cancer: a review
title_sort artificial intelligence in high dose rate brachytherapy treatment planning for cervical cancer a review
topic artificial intelligence (AI)
cervical cancer
high-dose-rate brachytherapy (HDR-BT)
treatment planning
deep learning (DL)
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1507592/full
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