Comprehensive analysis of molecular markers linked to antimalarial drug resistance in Plasmodium falciparum in Northern, Northeastern and Eastern Uganda

Comprehensive analysis of molecular markers linked to antimalarial drug resistance in Plasmodium falciparum in Northern, Northeastern and Eastern Uganda

Abstract Background In Uganda, antimalarial resistance in Plasmodium falciparum poses serious public health and treatment challenges. Globally, recent data have highlighted the roles of following genes in malaria resistance: Plasmodium falciparum dihydrofolate reductase (Pfdhfr), Plasmodium falcipar...

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Main Authors: Peter Olupot-Olupot, George Paasi, Thomas Katairo, Jimmy Patrick Alunyo, Alice Nakiyemba, Gilbert Gilibrays Ocen, Stephen Pande, Florance Alaroker, William Okiror, Emmaluel Ocen, Alex Oula, Charles Benard Okalebo, Ongodia Paul, Denis Amorut, Stephen Tukwasibwe, Susan Nabadda Ndidde, Isaac Sewanyana, Samuel L. Nsobya
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Malaria Journal
Subjects:
Antimalarial resistance
Uganda
Pfk13
Pfdhfr
Pfdhps Pfmdr1
Pfcrt
Online Access:https://doi.org/10.1186/s12936-025-05439-x
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