Serum albumin and blood haemoglobin: Do they have any cost-effective predictive value in assessing the functional outcome of acute ischaemic stroke in the present era?

Background: The available prognostic indicators of stroke at present are based on neurological findings. There are not enough cost-effective and feasible blood biomarkers in assessing functional outcomes in acute ischaemic stroke. Methods: In this prospective observational study (n = 223) predictive...

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Bibliographic Details
Main Authors: H. A. Krishnamurthy, S. Monisha
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Journal of Clinical and Scientific Research
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Online Access:https://journals.lww.com/10.4103/jcsr.jcsr_240_22
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Summary:Background: The available prognostic indicators of stroke at present are based on neurological findings. There are not enough cost-effective and feasible blood biomarkers in assessing functional outcomes in acute ischaemic stroke. Methods: In this prospective observational study (n = 223) predictive value of serum albumin and blood haemoglobin levels in assessing the functional outcome in subjects with acute ischaemic stroke was studied. The subjects were followed up for 3 months from the day of admission. The outcomes were assessed on day 1, day 7 and end of 3 months of the onset of acute ischaemic stroke using Modified Rankin Scale (MRS). Results: The mean serum albumin level was 2.8 ± 0.5 g/dL and haemoglobin level was 9.5 ± 1.9 g/dL in severe acute ischaemic stroke subjects. The 39.46% of acute ischaemic stroke subjects were having serum albumin of 2.9 ± 0.5 g/dL and Hb% of 9.8 ± 1.7 g/dL with MRS score of more than 3 with poor prognosis after 3 months of follow-up (P value < 0.05). Conclusions: The serum albumin and blood Hb levels are cost-effective and highly feasible blood biomarkers in assessing the prognosis in subjects with acute ischaemic stroke.
ISSN:2277-5706
2277-8357