Amyloid β (Aβ) inhibits retinal angiogenesis in Alzheimer's disease via LncRNA-XIST/miRNA-126-5p/VEGF axis

Amyloid β (Aβ) inhibits retinal angiogenesis in Alzheimer's disease via LncRNA-XIST/miRNA-126-5p/VEGF axis

Alzheimer's disease (AD) is often accompanied by retinal lesions, in which Amyloid β (Aβ) is a key mediator. Vascular dysfunction is always associated with the malignant progression of AD, but the precise mechanisms remain poorly understood. The aim of this study is to investigate how Aβ regula...

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Bibliographic Details
Main Authors: Bin Wang, Wenwei Li, Chaoyang Hong, Fangfang Jin, Baisheng Xu, Zhongwei Guo, Shuyang Chen, Qi Zhang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Immunobiology
Subjects:
Alzheimer's disease
Retinopathy
Amyloid β
LncRNA-XIST
miR-126-5p
VEGF
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298525002311
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