Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin
The rapid proliferation of antimicrobial resistance has emerged as one of the most pressing animal and public health challenges of our time. Probiotics, extensively employed in human and veterinary medicine, are instrumental in maintaining a balanced microbiome and mitigating its disruption during a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-03-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/12/3/217 |
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| author | Ádám Kerek István Román Ábel Szabó Nikolett Palkovicsné Pézsa Ákos Jerzsele |
| author_facet | Ádám Kerek István Román Ábel Szabó Nikolett Palkovicsné Pézsa Ákos Jerzsele |
| author_sort | Ádám Kerek |
| collection | DOAJ |
| description | The rapid proliferation of antimicrobial resistance has emerged as one of the most pressing animal and public health challenges of our time. Probiotics, extensively employed in human and veterinary medicine, are instrumental in maintaining a balanced microbiome and mitigating its disruption during antibiotic therapy. While their numerous benefits are well documented, probiotics also present potential risks, notably the capacity to harbor antimicrobial resistance genes. This genetic reservoir could contribute to the emergence and spread of antimicrobial resistance by facilitating the horizontal transfer of resistance genes to pathogenic bacteria within the gut. This review critically examines the presence of antimicrobial resistance genes in commonly used probiotic strains, explores the underlying mechanisms of resistance, and provides a balanced analysis of the benefits and risks associated with their use. By addressing these dual aspects, this paper highlights the need for vigilant evaluation of probiotics to preserve their therapeutic potential while minimizing public health risks. |
| format | Article |
| id | doaj-art-9c77d6310d7e413a89bf4f1abcdfd4dc |
| institution | DOAJ |
| issn | 2306-7381 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj-art-9c77d6310d7e413a89bf4f1abcdfd4dc2025-08-20T02:43:10ZengMDPI AGVeterinary Sciences2306-73812025-03-0112321710.3390/vetsci12030217Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the CoinÁdám Kerek0István Román1Ábel Szabó2Nikolett Palkovicsné Pézsa3Ákos Jerzsele4Department of Pharmacology and Toxicology, University of Veterinary Medicine, István utca 2, H-1078 Budapest, HungaryDepartment of Pharmacology and Toxicology, University of Veterinary Medicine, István utca 2, H-1078 Budapest, HungaryDepartment of Pharmacology and Toxicology, University of Veterinary Medicine, István utca 2, H-1078 Budapest, HungaryDepartment of Pharmacology and Toxicology, University of Veterinary Medicine, István utca 2, H-1078 Budapest, HungaryDepartment of Pharmacology and Toxicology, University of Veterinary Medicine, István utca 2, H-1078 Budapest, HungaryThe rapid proliferation of antimicrobial resistance has emerged as one of the most pressing animal and public health challenges of our time. Probiotics, extensively employed in human and veterinary medicine, are instrumental in maintaining a balanced microbiome and mitigating its disruption during antibiotic therapy. While their numerous benefits are well documented, probiotics also present potential risks, notably the capacity to harbor antimicrobial resistance genes. This genetic reservoir could contribute to the emergence and spread of antimicrobial resistance by facilitating the horizontal transfer of resistance genes to pathogenic bacteria within the gut. This review critically examines the presence of antimicrobial resistance genes in commonly used probiotic strains, explores the underlying mechanisms of resistance, and provides a balanced analysis of the benefits and risks associated with their use. By addressing these dual aspects, this paper highlights the need for vigilant evaluation of probiotics to preserve their therapeutic potential while minimizing public health risks.https://www.mdpi.com/2306-7381/12/3/217veterinary probioticsbenefitsrisksantibiotic resistance genesARGsantimicrobial resistance |
| spellingShingle | Ádám Kerek István Román Ábel Szabó Nikolett Palkovicsné Pézsa Ákos Jerzsele Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin Veterinary Sciences veterinary probiotics benefits risks antibiotic resistance genes ARGs antimicrobial resistance |
| title | Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin |
| title_full | Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin |
| title_fullStr | Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin |
| title_full_unstemmed | Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin |
| title_short | Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin |
| title_sort | antibiotic resistance gene expression in veterinary probiotics two sides of the coin |
| topic | veterinary probiotics benefits risks antibiotic resistance genes ARGs antimicrobial resistance |
| url | https://www.mdpi.com/2306-7381/12/3/217 |
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