Abstraction-based segmental simulation of reaction networks using adaptive memoization

Abstract Background  Stochastic models are commonly employed in the system and synthetic biology to study the effects of stochastic fluctuations emanating from reactions involving species with low copy-numbers. Many important models feature complex dynamics, involving a state-space explosion, stiffn...

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Main Authors: Martin Helfrich, Roman Andriushchenko, Milan Češka, Jan Křetínský, Štefan Martiček, David Šafránek
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Bioinformatics
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Online Access:https://doi.org/10.1186/s12859-024-05966-5
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