Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B
Westerdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and β-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with...
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| Format: | Article |
| Language: | English |
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BMC
2012-12-01
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| Series: | IMA Fungus |
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| Online Access: | http://www.ingentaconnect.com/content/ima/imafung/2012/00000003/00000002/art00019 |
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| author | Ghada A Ebead David P. Overy Fabrice Berrué Russell G. Kerr |
| author_facet | Ghada A Ebead David P. Overy Fabrice Berrué Russell G. Kerr |
| author_sort | Ghada A Ebead |
| collection | DOAJ |
| description | Westerdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and β-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with 32, aseptate, dark colored, pronouncedly reniform ascospores having a concave central groove. The isolate was obtained from a red alga (Polysiphonia sp.) collected from the tidal zone in Canada at low tide. Organic extracts enriched in extrolites, obtained from fermentation on a rice-based media, inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), S. warneri, and Proteus vulgaris. Presented here is the identification of the compounds responsible for the observed antimicrobial activity, the taxonomic description of W. reniformis, and a dichotomous key to the known species of Westerdykella based on macro- and micromorphological characters. |
| format | Article |
| id | doaj-art-9c3e0b7367c64cafaea8c17df97c2d18 |
| institution | Kabale University |
| issn | 2210-6340 2210-6359 |
| language | English |
| publishDate | 2012-12-01 |
| publisher | BMC |
| record_format | Article |
| series | IMA Fungus |
| spelling | doaj-art-9c3e0b7367c64cafaea8c17df97c2d182025-02-02T09:34:28ZengBMCIMA Fungus2210-63402210-63592012-12-0132189201Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin BGhada A EbeadDavid P. OveryFabrice BerruéRussell G. KerrWesterdykella reniformis Ebead & Overy sp. nov. is described based on morphology and phylogenetic analyses using ITS, nLSU rDNA, and β-tubulin gene sequences. Westerdykella reniformis is characterized by the production of cleistothecioid ascomata, containing small globose to subglobose asci with 32, aseptate, dark colored, pronouncedly reniform ascospores having a concave central groove. The isolate was obtained from a red alga (Polysiphonia sp.) collected from the tidal zone in Canada at low tide. Organic extracts enriched in extrolites, obtained from fermentation on a rice-based media, inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium (VRE), S. warneri, and Proteus vulgaris. Presented here is the identification of the compounds responsible for the observed antimicrobial activity, the taxonomic description of W. reniformis, and a dichotomous key to the known species of Westerdykella based on macro- and micromorphological characters.http://www.ingentaconnect.com/content/ima/imafung/2012/00000003/00000002/art00019ANTIMICROBIAL SCREENINGASCOMYCOTAITS PHYLOGENYMULTIGENE PHYLOGENYSPORORMIACEAE |
| spellingShingle | Ghada A Ebead David P. Overy Fabrice Berrué Russell G. Kerr Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B IMA Fungus ANTIMICROBIAL SCREENING ASCOMYCOTA ITS PHYLOGENY MULTIGENE PHYLOGENY SPORORMIACEAE |
| title | Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B |
| title_full | Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B |
| title_fullStr | Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B |
| title_full_unstemmed | Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B |
| title_short | Westerdykella reniformis sp. nov., producing the antibiotic metabolites melinacidin Iv and chetracin B |
| title_sort | westerdykella reniformis sp nov producing the antibiotic metabolites melinacidin iv and chetracin b |
| topic | ANTIMICROBIAL SCREENING ASCOMYCOTA ITS PHYLOGENY MULTIGENE PHYLOGENY SPORORMIACEAE |
| url | http://www.ingentaconnect.com/content/ima/imafung/2012/00000003/00000002/art00019 |
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