Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis are a diverse group of systemic autoimmune disorders characterized by the presence of ANCA in sera, involving frequently kidney and lung. Its etiology and pathogenesis are not fully elucidated. Although existing treatment with glucoco...
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| Format: | Article |
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Editorial Department of Journal of Clinical Nephrology
2022-12-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.12.011 |
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| _version_ | 1849312250972602368 |
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| author | Wen Kai-lian Li Gui-sen Wang Li |
| author_facet | Wen Kai-lian Li Gui-sen Wang Li |
| author_sort | Wen Kai-lian |
| collection | DOAJ |
| description | Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis are a diverse group of systemic autoimmune disorders characterized by the presence of ANCA in sera, involving frequently kidney and lung. Its etiology and pathogenesis are not fully elucidated. Although existing treatment with glucocorticoids plus immunosuppressant has greatly improved the prognosis, it is prone to relapse after remission and often accompanied by serious adverse events. Basic treatment of glucocorticoids lacks uniformity and standardization in its applications and it is a major factor of treatment-related adverse events. This review summarized the applications of glucocorticoids for ANCA-associated vasculitis to provide references for clinical practices. |
| format | Article |
| id | doaj-art-9c36f9d9c09c498a8a7e4fe177f41d0c |
| institution | Kabale University |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2022-12-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-9c36f9d9c09c498a8a7e4fe177f41d0c2025-08-20T03:53:07ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902022-12-01221036104133236711Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitisWen Kai-lianLi Gui-senWang LiAnti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis are a diverse group of systemic autoimmune disorders characterized by the presence of ANCA in sera, involving frequently kidney and lung. Its etiology and pathogenesis are not fully elucidated. Although existing treatment with glucocorticoids plus immunosuppressant has greatly improved the prognosis, it is prone to relapse after remission and often accompanied by serious adverse events. Basic treatment of glucocorticoids lacks uniformity and standardization in its applications and it is a major factor of treatment-related adverse events. This review summarized the applications of glucocorticoids for ANCA-associated vasculitis to provide references for clinical practices.http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.12.011Antibodies, antineutrophil cytoplasmicVasculitisGlucocorticoids |
| spellingShingle | Wen Kai-lian Li Gui-sen Wang Li Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis Linchuang shenzangbing zazhi Antibodies, antineutrophil cytoplasmic Vasculitis Glucocorticoids |
| title | Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis |
| title_full | Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis |
| title_fullStr | Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis |
| title_full_unstemmed | Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis |
| title_short | Applications and challenges of glucocorticoids for anti-neutrophil cytoplasmic antibody-associated vasculitis |
| title_sort | applications and challenges of glucocorticoids for anti neutrophil cytoplasmic antibody associated vasculitis |
| topic | Antibodies, antineutrophil cytoplasmic Vasculitis Glucocorticoids |
| url | http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.12.011 |
| work_keys_str_mv | AT wenkailian applicationsandchallengesofglucocorticoidsforantineutrophilcytoplasmicantibodyassociatedvasculitis AT liguisen applicationsandchallengesofglucocorticoidsforantineutrophilcytoplasmicantibodyassociatedvasculitis AT wangli applicationsandchallengesofglucocorticoidsforantineutrophilcytoplasmicantibodyassociatedvasculitis |