Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019
Objective: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19). Methods: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptoma...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2022-03-01
|
| Series: | Medeniyet Medical Journal |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-47600 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832581974792863744 |
|---|---|
| author | Tayfun VURAL Burak BAYRAKTAR Suna YILDIRIM KARACA Ozan ODABAS Nisel YILMAZ Pınar SAMLIOGLU Mehmet OZEREN |
| author_facet | Tayfun VURAL Burak BAYRAKTAR Suna YILDIRIM KARACA Ozan ODABAS Nisel YILMAZ Pınar SAMLIOGLU Mehmet OZEREN |
| author_sort | Tayfun VURAL |
| collection | DOAJ |
| description | Objective: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19).
Methods: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptomatic according to their clinics at the time of application. COVID-19 was diagnosed using the real-time reverse transcriptase-polymerase chain reaction on the oropharyngeal and nasopharyngeal swabs. Asymptomatic and symptomatic patients were compared in terms of maternal and perinatal outcomes.
Results: Our study population consisted of 20 asymptomatic and 41 symptomatic patients with laboratory-confirmed COVID-19. The rate of primary cesarean section was more than twice in the symptomatic group (51.2%) than that of the asymptomatic group (20%) (p=0.019). Both groups are quite similar in terms of maternal [respiratory support, COVID-19-related treatment, and intensive care unit (ICU) admission], perinatal (preterm delivery, preterm premature rupture of membrane, preeclampsia, and mode of delivery), and neonatal outcomes [birth weight, Apgar scores, neonatal ICU (NICU) admission]. The rate of total cesarean section in the asymptomatic group (75%) was statistically similar to the symptomatic group (83%) (p=0.464). The NICU admission rate was found to be similar in the asymptomatic (54.2%) and symptomatic groups (50%) (p=0.858). However, NICU admissions were more frequent in the symptomatic group due to respiratory distress (p=0.032). The breastfeeding rate is higher in the asymptomatic pregnant group as expected (p=0.015). Additionally, the ferritin level was significantly lower in the asymptomatic group (p=0.006).
Conclusions: The rate of primary cesarean section is quite high in symptomatic patients with COVID-19. Additionally, the total cesarean section rate was extremely high in both groups. We expected more adverse outcomes in symptomatic patients; however, we found similar maternal, perinatal, and neonatal outcomes between both groups. |
| format | Article |
| id | doaj-art-9c2eb3ccf0c44da98b16525b9da7e5d6 |
| institution | Kabale University |
| issn | 2149-2042 2149-4606 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Medeniyet Medical Journal |
| spelling | doaj-art-9c2eb3ccf0c44da98b16525b9da7e5d62025-01-30T07:15:45ZengGalenos Publishing HouseMedeniyet Medical Journal2149-20422149-46062022-03-01371445310.4274/MMJ.galenos.2022.47600MEDJ-47600Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019Tayfun VURAL0Burak BAYRAKTAR1Suna YILDIRIM KARACA2Ozan ODABAS3Nisel YILMAZ4Pınar SAMLIOGLU5Mehmet OZEREN6University of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Obstetrics and Gynecology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Obstetrics and Gynecology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Obstetrics and Gynecology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Obstetrics and Gynecology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Clinical Microbiology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Clinical Microbiology, Izmir, TurkeyUniversity of Health Sciences Turkey, Tepecik Training and Research Hospital, Clinic of Perinatology, Izmir, TurkeyObjective: This study aimed to compare the postpartum outcomes of asymptomatic and symptomatic patients with coronavirus disease-2019 (COVID-19). Methods: This retrospective cohort study included pregnant women with COVID-19. Pregnant women were categorized into two sets as asymptomatic and symptomatic according to their clinics at the time of application. COVID-19 was diagnosed using the real-time reverse transcriptase-polymerase chain reaction on the oropharyngeal and nasopharyngeal swabs. Asymptomatic and symptomatic patients were compared in terms of maternal and perinatal outcomes. Results: Our study population consisted of 20 asymptomatic and 41 symptomatic patients with laboratory-confirmed COVID-19. The rate of primary cesarean section was more than twice in the symptomatic group (51.2%) than that of the asymptomatic group (20%) (p=0.019). Both groups are quite similar in terms of maternal [respiratory support, COVID-19-related treatment, and intensive care unit (ICU) admission], perinatal (preterm delivery, preterm premature rupture of membrane, preeclampsia, and mode of delivery), and neonatal outcomes [birth weight, Apgar scores, neonatal ICU (NICU) admission]. The rate of total cesarean section in the asymptomatic group (75%) was statistically similar to the symptomatic group (83%) (p=0.464). The NICU admission rate was found to be similar in the asymptomatic (54.2%) and symptomatic groups (50%) (p=0.858). However, NICU admissions were more frequent in the symptomatic group due to respiratory distress (p=0.032). The breastfeeding rate is higher in the asymptomatic pregnant group as expected (p=0.015). Additionally, the ferritin level was significantly lower in the asymptomatic group (p=0.006). Conclusions: The rate of primary cesarean section is quite high in symptomatic patients with COVID-19. Additionally, the total cesarean section rate was extremely high in both groups. We expected more adverse outcomes in symptomatic patients; however, we found similar maternal, perinatal, and neonatal outcomes between both groups.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-47600sars-cov-2asymptomatic infectioncoronaviruscovid-19pregnancyvertical transmission |
| spellingShingle | Tayfun VURAL Burak BAYRAKTAR Suna YILDIRIM KARACA Ozan ODABAS Nisel YILMAZ Pınar SAMLIOGLU Mehmet OZEREN Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 Medeniyet Medical Journal sars-cov-2 asymptomatic infection coronavirus covid-19 pregnancy vertical transmission |
| title | Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 |
| title_full | Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 |
| title_fullStr | Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 |
| title_full_unstemmed | Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 |
| title_short | Comparison of Maternal, Perinatal, and Neonatal Outcomes of Asymptomatic and Symptomatic Pregnant Women with Coronavirus Disease-2019 |
| title_sort | comparison of maternal perinatal and neonatal outcomes of asymptomatic and symptomatic pregnant women with coronavirus disease 2019 |
| topic | sars-cov-2 asymptomatic infection coronavirus covid-19 pregnancy vertical transmission |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=medeniyet&un=MEDJ-47600 |
| work_keys_str_mv | AT tayfunvural comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT burakbayraktar comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT sunayildirimkaraca comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT ozanodabas comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT niselyilmaz comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT pınarsamlioglu comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 AT mehmetozeren comparisonofmaternalperinatalandneonataloutcomesofasymptomaticandsymptomaticpregnantwomenwithcoronavirusdisease2019 |