Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus

A 38-year-old female with systemic lupus erythematosus presented with abdominal pain, diarrhea and iron-deficient anemia. Computed tomogram showed a 2x4 cm inhomogeneous lesion of the right adnexa. An unusual mass was identified extending from the appendiceal orifice at colonoscopy, and an 8 cm tubu...

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Main Authors: Debrah A Wirtzfeld, Lorne M Price, Maire A Duggan, Shaun AC Medlicott, Francis R Sutherland
Format: Article
Language:English
Published: Wiley 1998-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1998/317346
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author Debrah A Wirtzfeld
Lorne M Price
Maire A Duggan
Shaun AC Medlicott
Francis R Sutherland
author_facet Debrah A Wirtzfeld
Lorne M Price
Maire A Duggan
Shaun AC Medlicott
Francis R Sutherland
author_sort Debrah A Wirtzfeld
collection DOAJ
description A 38-year-old female with systemic lupus erythematosus presented with abdominal pain, diarrhea and iron-deficient anemia. Computed tomogram showed a 2x4 cm inhomogeneous lesion of the right adnexa. An unusual mass was identified extending from the appendiceal orifice at colonoscopy, and an 8 cm tubular appendix, apparently prolapsed into the cecum, was identified at celiotomy. An appendectomy with cecectomy was performed. On cut section, mucin was extruded from the lumen of the appendix. A mucinous neoplasm of the appendix with mucinous dissection to the serosal surface was reported at the time of frozen section. No gross ovarian pathology or peritoneal implants were noted. Cystadenoma with associated mucocele formation was verified by permanent histology. Mucocele of the vermiform appendix is a rare condition associated with neoplastic transformation in approximately 75% of all cases. Benign mucinous cystadenoma of the appendix should be differentiated from cystadenocarcinoma by frozen section at the time of celiotomy to ensure appropriate treatment. While systemic lupus erythematosus can lead to cutaneous mucinosis, an association with mucinous cystadenoma of the appendix has not been previously reported. Surveillance for metachronous colonic neoplasms is warranted in patients diagnosed with a mucinous neoplasm of the appendix.
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spelling doaj-art-9c2d5c3920be41679f0a68e95aef29932025-02-03T05:44:16ZengWileyCanadian Journal of Gastroenterology0835-79001998-01-0112857357610.1155/1998/317346Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus ErthematosusDebrah A Wirtzfeld0Lorne M Price1Maire A Duggan2Shaun AC Medlicott3Francis R Sutherland4Department of General Surgery, University of Calgary, Calgary, Alberta, CanadaDepartment of Internal Medicine , University of Calgary, Calgary, Alberta, CanadaDepartment of Pathology, University of Calgary, Calgary, Alberta, CanadaDepartment of Pathology, University of Calgary, Calgary, Alberta, CanadaDepartment of General Surgery, University of Calgary, Calgary, Alberta, CanadaA 38-year-old female with systemic lupus erythematosus presented with abdominal pain, diarrhea and iron-deficient anemia. Computed tomogram showed a 2x4 cm inhomogeneous lesion of the right adnexa. An unusual mass was identified extending from the appendiceal orifice at colonoscopy, and an 8 cm tubular appendix, apparently prolapsed into the cecum, was identified at celiotomy. An appendectomy with cecectomy was performed. On cut section, mucin was extruded from the lumen of the appendix. A mucinous neoplasm of the appendix with mucinous dissection to the serosal surface was reported at the time of frozen section. No gross ovarian pathology or peritoneal implants were noted. Cystadenoma with associated mucocele formation was verified by permanent histology. Mucocele of the vermiform appendix is a rare condition associated with neoplastic transformation in approximately 75% of all cases. Benign mucinous cystadenoma of the appendix should be differentiated from cystadenocarcinoma by frozen section at the time of celiotomy to ensure appropriate treatment. While systemic lupus erythematosus can lead to cutaneous mucinosis, an association with mucinous cystadenoma of the appendix has not been previously reported. Surveillance for metachronous colonic neoplasms is warranted in patients diagnosed with a mucinous neoplasm of the appendix.http://dx.doi.org/10.1155/1998/317346
spellingShingle Debrah A Wirtzfeld
Lorne M Price
Maire A Duggan
Shaun AC Medlicott
Francis R Sutherland
Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
Canadian Journal of Gastroenterology
title Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
title_full Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
title_fullStr Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
title_full_unstemmed Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
title_short Mucinous Cystadenoma of the Appendix in a Patient with Systemic Lupus Erthematosus
title_sort mucinous cystadenoma of the appendix in a patient with systemic lupus erthematosus
url http://dx.doi.org/10.1155/1998/317346
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AT maireaduggan mucinouscystadenomaoftheappendixinapatientwithsystemiclupuserthematosus
AT shaunacmedlicott mucinouscystadenomaoftheappendixinapatientwithsystemiclupuserthematosus
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