Resistance to the Beneficial Metabolic Effects and Hepatic Antioxidant Defense Actions of Fibroblast Growth Factor 21 Treatment in Growth Hormone-Overexpressing Transgenic Mice
Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response, and energy homeostasis, but with limited mechanistic insight. FGF21 treatment has been shown to inhibit hepatic growth hormone (GH) intracellul...
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Main Authors: | Ravneet K. Boparai, Oge Arum, Johanna G. Miquet, Michal M. Masternak, Andrzej Bartke, Romesh K. Khardori |
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Format: | Article |
Language: | English |
Published: |
Wiley
2015-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2015/282375 |
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