Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging

Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result....

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Main Authors: Tarek M. Mousa, Oluwaseun A. Akinseye, Ketevan Berekashvili, Olakunle O. Akinboboye
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2015/742658
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author Tarek M. Mousa
Oluwaseun A. Akinseye
Ketevan Berekashvili
Olakunle O. Akinboboye
author_facet Tarek M. Mousa
Oluwaseun A. Akinseye
Ketevan Berekashvili
Olakunle O. Akinboboye
author_sort Tarek M. Mousa
collection DOAJ
description Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and central BP measurements were completed at first visit and at 4 weeks in 65 healthy volunteers who were at least 40 years old and not on medication. Subjects were divided into two groups of normotensives and prehypertensives based on JNC-7 criteria and LVM was obtained using cardiac magnetic resonance imaging. Prehypertensives had significantly higher LVMI compared to normotensives (P<0.01). Brachial and central BP also both positively correlate with LVMI (r=0.460, P<0.01; r=0.318, P=0.012, resp.) in both groups and neither method was superior to the other. After multivariate regression analysis and adjusting for cardiovascular risk factors, prehypertension remained an independent determinant of LVM. Conclusion. Prehypertension is associated with cardiovascular target organ damage, and central BP was not superior to brachial BP or vice versa for association with LVMI.
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publishDate 2015-01-01
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series International Journal of Hypertension
spelling doaj-art-9c06bba2fd3a4e4c9a7817d90f23d3f02025-08-20T02:20:16ZengWileyInternational Journal of Hypertension2090-03842090-03922015-01-01201510.1155/2015/742658742658Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance ImagingTarek M. Mousa0Oluwaseun A. Akinseye1Ketevan Berekashvili2Olakunle O. Akinboboye3Queens Heart Institute, 234 36 Merrick Boulevard, Laurelton, NY 11422, USADepartment of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, 82 68 164th Street, Jamaica, NY 11432, USADepartment of Neurology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USAQueens Heart Institute, 234 36 Merrick Boulevard, Laurelton, NY 11422, USAIntroduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and central BP measurements were completed at first visit and at 4 weeks in 65 healthy volunteers who were at least 40 years old and not on medication. Subjects were divided into two groups of normotensives and prehypertensives based on JNC-7 criteria and LVM was obtained using cardiac magnetic resonance imaging. Prehypertensives had significantly higher LVMI compared to normotensives (P<0.01). Brachial and central BP also both positively correlate with LVMI (r=0.460, P<0.01; r=0.318, P=0.012, resp.) in both groups and neither method was superior to the other. After multivariate regression analysis and adjusting for cardiovascular risk factors, prehypertension remained an independent determinant of LVM. Conclusion. Prehypertension is associated with cardiovascular target organ damage, and central BP was not superior to brachial BP or vice versa for association with LVMI.http://dx.doi.org/10.1155/2015/742658
spellingShingle Tarek M. Mousa
Oluwaseun A. Akinseye
Ketevan Berekashvili
Olakunle O. Akinboboye
Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
International Journal of Hypertension
title Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
title_full Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
title_fullStr Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
title_full_unstemmed Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
title_short Correlation of Prehypertension with Left Ventricular Mass Assessed by Cardiac Magnetic Resonance Imaging
title_sort correlation of prehypertension with left ventricular mass assessed by cardiac magnetic resonance imaging
url http://dx.doi.org/10.1155/2015/742658
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