Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
Valvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we p...
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2014-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1155/2014/216291 |
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author | Mahnoosh Foroughi Manouchehr Hekmat Mohsen Ghorbani Hamid Ghaderi Masoud Majidi Mahmood Beheshti |
author_facet | Mahnoosh Foroughi Manouchehr Hekmat Mohsen Ghorbani Hamid Ghaderi Masoud Majidi Mahmood Beheshti |
author_sort | Mahnoosh Foroughi |
collection | DOAJ |
description | Valvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we provide a systematic review of the literature on mitral valve surgery in the presence of Libman-Sacks endocarditis because its challenge on surgical options continues. Surgical decision depends on structural involvement of mitral valve and presence of active lupus nephritis and antiphospholipid antibody syndrome. Review of the literature has also shown that outcome is good in most SLE patients who have undergone valvular surgery, but association of antiphospholipid antibody syndrome with SLE has negative impact on the outcome. |
format | Article |
id | doaj-art-9be5b1cc189c469c9e8c7ce59485cc9a |
institution | Kabale University |
issn | 2356-6140 1537-744X |
language | English |
publishDate | 2014-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-9be5b1cc189c469c9e8c7ce59485cc9a2025-02-03T01:32:17ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/216291216291Mitral Valve Surgery in Patients with Systemic Lupus ErythematosusMahnoosh Foroughi0Manouchehr Hekmat1Mohsen Ghorbani2Hamid Ghaderi3Masoud Majidi4Mahmood Beheshti5Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranValvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we provide a systematic review of the literature on mitral valve surgery in the presence of Libman-Sacks endocarditis because its challenge on surgical options continues. Surgical decision depends on structural involvement of mitral valve and presence of active lupus nephritis and antiphospholipid antibody syndrome. Review of the literature has also shown that outcome is good in most SLE patients who have undergone valvular surgery, but association of antiphospholipid antibody syndrome with SLE has negative impact on the outcome.http://dx.doi.org/10.1155/2014/216291 |
spellingShingle | Mahnoosh Foroughi Manouchehr Hekmat Mohsen Ghorbani Hamid Ghaderi Masoud Majidi Mahmood Beheshti Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus The Scientific World Journal |
title | Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus |
title_full | Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus |
title_fullStr | Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus |
title_full_unstemmed | Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus |
title_short | Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus |
title_sort | mitral valve surgery in patients with systemic lupus erythematosus |
url | http://dx.doi.org/10.1155/2014/216291 |
work_keys_str_mv | AT mahnooshforoughi mitralvalvesurgeryinpatientswithsystemiclupuserythematosus AT manouchehrhekmat mitralvalvesurgeryinpatientswithsystemiclupuserythematosus AT mohsenghorbani mitralvalvesurgeryinpatientswithsystemiclupuserythematosus AT hamidghaderi mitralvalvesurgeryinpatientswithsystemiclupuserythematosus AT masoudmajidi mitralvalvesurgeryinpatientswithsystemiclupuserythematosus AT mahmoodbeheshti mitralvalvesurgeryinpatientswithsystemiclupuserythematosus |