Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus

Valvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we p...

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Main Authors: Mahnoosh Foroughi, Manouchehr Hekmat, Mohsen Ghorbani, Hamid Ghaderi, Masoud Majidi, Mahmood Beheshti
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/216291
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author Mahnoosh Foroughi
Manouchehr Hekmat
Mohsen Ghorbani
Hamid Ghaderi
Masoud Majidi
Mahmood Beheshti
author_facet Mahnoosh Foroughi
Manouchehr Hekmat
Mohsen Ghorbani
Hamid Ghaderi
Masoud Majidi
Mahmood Beheshti
author_sort Mahnoosh Foroughi
collection DOAJ
description Valvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we provide a systematic review of the literature on mitral valve surgery in the presence of Libman-Sacks endocarditis because its challenge on surgical options continues. Surgical decision depends on structural involvement of mitral valve and presence of active lupus nephritis and antiphospholipid antibody syndrome. Review of the literature has also shown that outcome is good in most SLE patients who have undergone valvular surgery, but association of antiphospholipid antibody syndrome with SLE has negative impact on the outcome.
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id doaj-art-9be5b1cc189c469c9e8c7ce59485cc9a
institution Kabale University
issn 2356-6140
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series The Scientific World Journal
spelling doaj-art-9be5b1cc189c469c9e8c7ce59485cc9a2025-02-03T01:32:17ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/216291216291Mitral Valve Surgery in Patients with Systemic Lupus ErythematosusMahnoosh Foroughi0Manouchehr Hekmat1Mohsen Ghorbani2Hamid Ghaderi3Masoud Majidi4Mahmood Beheshti5Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranCardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Modarres Hospital, Saadat Abad, Tehran 19987 34383, IranValvular heart disease is the common cardiac manifestation of systemic lupus erythematosus (SLE) with a tendency for mitral valve regurgitation. In this study we report a case of mitral valve replacement for mitral stenosis caused by Libman-Sacks endocarditis in the setting of SLE. In addition, we provide a systematic review of the literature on mitral valve surgery in the presence of Libman-Sacks endocarditis because its challenge on surgical options continues. Surgical decision depends on structural involvement of mitral valve and presence of active lupus nephritis and antiphospholipid antibody syndrome. Review of the literature has also shown that outcome is good in most SLE patients who have undergone valvular surgery, but association of antiphospholipid antibody syndrome with SLE has negative impact on the outcome.http://dx.doi.org/10.1155/2014/216291
spellingShingle Mahnoosh Foroughi
Manouchehr Hekmat
Mohsen Ghorbani
Hamid Ghaderi
Masoud Majidi
Mahmood Beheshti
Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
The Scientific World Journal
title Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
title_full Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
title_fullStr Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
title_full_unstemmed Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
title_short Mitral Valve Surgery in Patients with Systemic Lupus Erythematosus
title_sort mitral valve surgery in patients with systemic lupus erythematosus
url http://dx.doi.org/10.1155/2014/216291
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AT manouchehrhekmat mitralvalvesurgeryinpatientswithsystemiclupuserythematosus
AT mohsenghorbani mitralvalvesurgeryinpatientswithsystemiclupuserythematosus
AT hamidghaderi mitralvalvesurgeryinpatientswithsystemiclupuserythematosus
AT masoudmajidi mitralvalvesurgeryinpatientswithsystemiclupuserythematosus
AT mahmoodbeheshti mitralvalvesurgeryinpatientswithsystemiclupuserythematosus