The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review
Neurons and glia respond to acute injury by participating in the CNS innate immune response. This involves the recognition and clearance of “not self ” pathogens and “altered self ” apoptotic cells. Phagocytic receptors (CD14, CD36, TLR–4) clear “not self” pathogens; neurons and glia express “deat...
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Main Authors: | M. R. Griffiths, P. Gasque, J. W. Neal |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | International Journal of Inflammation |
Online Access: | http://dx.doi.org/10.4061/2010/151097 |
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