A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology
Methotrexate (MTX) is a folate analog widely used against a range of diseases including malignancies and autoimmune disorders. Its high effectiveness-price ratio also won extensive application in ophthalmology. On the other hand, although MTX has an excellent pharmacological efficacy, MTX associated...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/1537689 |
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| _version_ | 1832565872925868032 |
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| author | Ge Wang Xiaoyan Peng |
| author_facet | Ge Wang Xiaoyan Peng |
| author_sort | Ge Wang |
| collection | DOAJ |
| description | Methotrexate (MTX) is a folate analog widely used against a range of diseases including malignancies and autoimmune disorders. Its high effectiveness-price ratio also won extensive application in ophthalmology. On the other hand, although MTX has an excellent pharmacological efficacy, MTX associated side effects in clinical use, which vary from patient to patient, are nonnegligible. There is no comparatively systematic review on MTX associated side effects and its risk factors. This review aimed to reveal novel clinical approaches of MTX and its adverse effects in order to provide a reference for ophthalmic scholars in clinical application of MTX. |
| format | Article |
| id | doaj-art-9bcee3cc5ba1406bb0d06731eb36d950 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-9bcee3cc5ba1406bb0d06731eb36d9502025-02-03T01:06:23ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/15376891537689A Review of Clinical Applications and Side Effects of Methotrexate in OphthalmologyGe Wang0Xiaoyan Peng1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, ChinaBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab, Beijing, ChinaMethotrexate (MTX) is a folate analog widely used against a range of diseases including malignancies and autoimmune disorders. Its high effectiveness-price ratio also won extensive application in ophthalmology. On the other hand, although MTX has an excellent pharmacological efficacy, MTX associated side effects in clinical use, which vary from patient to patient, are nonnegligible. There is no comparatively systematic review on MTX associated side effects and its risk factors. This review aimed to reveal novel clinical approaches of MTX and its adverse effects in order to provide a reference for ophthalmic scholars in clinical application of MTX.http://dx.doi.org/10.1155/2020/1537689 |
| spellingShingle | Ge Wang Xiaoyan Peng A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology Journal of Ophthalmology |
| title | A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology |
| title_full | A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology |
| title_fullStr | A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology |
| title_full_unstemmed | A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology |
| title_short | A Review of Clinical Applications and Side Effects of Methotrexate in Ophthalmology |
| title_sort | review of clinical applications and side effects of methotrexate in ophthalmology |
| url | http://dx.doi.org/10.1155/2020/1537689 |
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