The impact of circWWC3 on neoadjuvant therapy for triple-negative breast cancer and the construction of a nomogram for predicting pathological complete response after neoadjuvant therapy

The impact of circWWC3 on neoadjuvant therapy for triple-negative breast cancer and the construction of a nomogram for predicting pathological complete response after neoadjuvant therapy

BackgroundThe introduction of novel strategies for neoadjuvant therapy (NAT) has significantly enhanced the rate of pathological complete response (pCR) in patients with triple-negative breast cancer (TNBC). However, due to tumor heterogeneity, some patients continue to experience poor treatment eff...

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Bibliographic Details
Main Authors: Haoqi Wang, Hongbo Liu, Shan Gao, Lijia Wang, Zihao Bai, Yi Zhang, Peijin Zhang, Fei Liu, Cuizhi Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
triple-negative breast cancer
circWWC3
neoadjuvant therapy
pathological complete response
nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1564693/full
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