Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo

Investigation of the antioxidant status and the number of double-stranded DNA breaks in models of brain tumor lesion by metastases of non-small cell lung cancer in vivo

Purpose of the study. Evaluation of the antioxidant status and DNA damage in tissues of subcutaneous xenografts of non-small cell lung cancer and in peritumoral tissues created using the A549 and H1299 cell cultures.Materials and methods. The study included 35 intact male Balb/c Nude immunodeficient...

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Bibliographic Details
Main Authors: E. V. Zaikina, I. A. Alliluev, Yu. N. Lazutin, Yu. V. Przhedetskiy, Yu. S. Shatova, M. A. Engibaryan, E. F. Komarova, D. A. Kharagezov, A. V. Galina, A. A. Kiblitskaya, M. V. Mindar, L. Z. Kurbanova
Format: Article
Language:Russian
Published: QUASAR, LLC 2022-12-01
Series:Исследования и практика в медицине
Subjects:
oxidative stress
antioxidant enzymes
xenografts
cdx models
Online Access:https://www.rpmj.ru/rpmj/article/view/799
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