A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma

A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma

Abstract Lipid storage and epigenetic dysregulation are key features for clear cell renal carcinoma (ccRCC). However, the interplay between fatty acid metabolism and epigenetics in ccRCC remains to be further demonstrated. Here, the landscape of active enhancers is profiled in paired ccRCC samples a...

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Main Authors: Zhou Ye, Qi‐Xin Hu, Ming‐Liang Wei, Ji‐Dong Chen, Jia Shi, Ning‐Rong Yang, Lu Jiang, Jian Chen, Zhi‐Yuan Chen, Wei‐Min Yu, Yu Xiao, Kai‐Yu Qian, Zilin Xu, Zhong Wang, Wen‐Lu Qi, Xin‐Yi Xiao, Yu‐Yu Duan, Yong Xiao, Lian‐Yun Li, Lin‐Gao Ju, Ming‐Kai Chen, Min Wu
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Advanced Science
Subjects:
ccRCC
enhancer
FABP5
H3K27ac
lipid droplet
Online Access:https://doi.org/10.1002/advs.202504532
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