The Role of Vaccination in the Control of SARS

The Role of Vaccination in the Control of SARS

We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels o...

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Bibliographic Details
Main Authors: Julijana Gjorgjieva, Kelly Smith, Gerardo Chowell, Fabio Sánchez, Jessica Snyder, Carlos Castillo-Chavez
Format: Article
Language:English
Published: AIMS Press 2005-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
vaccination
isolation.
severe acute respiratory syndrome (sars)
contact tracing
mathematical model
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.753
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Summary:We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels of self-isolation among untraced infected individuals are explored. Bounds on the proportion of pre-outbreak successfully vaccinated individuals are provided using the the basic reproductive number. Uncertainty and sensitivity analyses on the reproductive number are carried out. The final epidemic size under different vaccination scenarios is computed.
ISSN:1551-0018

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