Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice

Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice

Summary: The hippocampus, a critical brain structure for spatial learning and memory, is susceptible to neurodegenerative disorders such as Alzheimer’s disease (AD). Utilizing APPswe/PSEN1dE9 (APP/PS1) mice, we investigated neurophysiological mechanisms underlying AD-associated cognitive impairments...

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Bibliographic Details
Main Authors: Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J. Kim, Jeiwon Cho, Yeowool Huh
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Molecular biology
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422402858X
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