Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications
Collagen-based wound dressings have developed as an essential component of contemporary wound care, utilizing collagen’s inherent properties to promote healing. This review thoroughly analyzes collagen dressing advances, examining different formulations such as hydrogels, films, and foams that enhan...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/11/4/271 |
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| author | Adina Alberts Andreea Gabriela Bratu Adelina-Gabriela Niculescu Alexandru Mihai Grumezescu |
| author_facet | Adina Alberts Andreea Gabriela Bratu Adelina-Gabriela Niculescu Alexandru Mihai Grumezescu |
| author_sort | Adina Alberts |
| collection | DOAJ |
| description | Collagen-based wound dressings have developed as an essential component of contemporary wound care, utilizing collagen’s inherent properties to promote healing. This review thoroughly analyzes collagen dressing advances, examining different formulations such as hydrogels, films, and foams that enhance wound care. The important processes by which collagen promotes healing (e.g., promoting angiogenesis, encouraging cell proliferation, and offering structural support) are discussed to clarify its function in tissue regeneration. The effectiveness and adaptability of collagen dressings are demonstrated via clinical applications investigated in acute and chronic wounds. Additionally, commercially accessible collagen-based skin healing treatments are discussed, demonstrating their practical use in healthcare settings. Despite the progress, the study discusses the obstacles and restrictions encountered in producing and adopting collagen-based dressings, such as the difficulties of manufacturing and financial concerns. Finally, the current landscape’s insights indicate future research possibilities for collagen dressing optimization, bioactive agent integration, and overcoming existing constraints. This analysis highlights the potential of collagen-based innovations to improve wound treatment methods and patient care. |
| format | Article |
| id | doaj-art-9b07a36fa94f4748a1a6db8681f240b9 |
| institution | DOAJ |
| issn | 2310-2861 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj-art-9b07a36fa94f4748a1a6db8681f240b92025-08-20T03:13:49ZengMDPI AGGels2310-28612025-04-0111427110.3390/gels11040271Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical ApplicationsAdina Alberts0Andreea Gabriela Bratu1Adelina-Gabriela Niculescu2Alexandru Mihai Grumezescu3Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, RomaniaFaculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gh. Polizu St. 1-7, 060042 Bucharest, RomaniaFaculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gh. Polizu St. 1-7, 060042 Bucharest, RomaniaFaculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, Gh. Polizu St. 1-7, 060042 Bucharest, RomaniaCollagen-based wound dressings have developed as an essential component of contemporary wound care, utilizing collagen’s inherent properties to promote healing. This review thoroughly analyzes collagen dressing advances, examining different formulations such as hydrogels, films, and foams that enhance wound care. The important processes by which collagen promotes healing (e.g., promoting angiogenesis, encouraging cell proliferation, and offering structural support) are discussed to clarify its function in tissue regeneration. The effectiveness and adaptability of collagen dressings are demonstrated via clinical applications investigated in acute and chronic wounds. Additionally, commercially accessible collagen-based skin healing treatments are discussed, demonstrating their practical use in healthcare settings. Despite the progress, the study discusses the obstacles and restrictions encountered in producing and adopting collagen-based dressings, such as the difficulties of manufacturing and financial concerns. Finally, the current landscape’s insights indicate future research possibilities for collagen dressing optimization, bioactive agent integration, and overcoming existing constraints. This analysis highlights the potential of collagen-based innovations to improve wound treatment methods and patient care.https://www.mdpi.com/2310-2861/11/4/271collagencollagen wound dressingchronic woundswound healingangiogenesispolymers |
| spellingShingle | Adina Alberts Andreea Gabriela Bratu Adelina-Gabriela Niculescu Alexandru Mihai Grumezescu Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications Gels collagen collagen wound dressing chronic wounds wound healing angiogenesis polymers |
| title | Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications |
| title_full | Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications |
| title_fullStr | Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications |
| title_full_unstemmed | Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications |
| title_short | Collagen-Based Wound Dressings: Innovations, Mechanisms, and Clinical Applications |
| title_sort | collagen based wound dressings innovations mechanisms and clinical applications |
| topic | collagen collagen wound dressing chronic wounds wound healing angiogenesis polymers |
| url | https://www.mdpi.com/2310-2861/11/4/271 |
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