Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo
In vivo optical imaging is being conducted in a variety of medical applications, including optical breast cancer imaging, functional brain imaging, endoscopy, exercise medicine, and monitoring the photodynamic therapy and progress of neoadjuvant chemotherapy. In the past three decades, in vivo diffu...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.3233/ACP-2012-0058 |
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| _version_ | 1832565399270457344 |
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| author | Yasaman Ardeshirpour Amir H. Gandjbakhche Laleh Najafizadeh |
| author_facet | Yasaman Ardeshirpour Amir H. Gandjbakhche Laleh Najafizadeh |
| author_sort | Yasaman Ardeshirpour |
| collection | DOAJ |
| description | In vivo optical imaging is being conducted in a variety of medical applications, including optical breast cancer imaging, functional brain imaging, endoscopy, exercise medicine, and monitoring the photodynamic therapy and progress of neoadjuvant chemotherapy. In the past three decades, in vivo diffuse optical breast cancer imaging has shown promising results in cancer detection, and monitoring the progress of neoadjuvant chemotherapy. The use of near infrared spectroscopy for functional brain imaging has been growing rapidly. In fluorescence imaging, the difference between autofluorescence of cancer lesions compared to normal tissues were used in endoscopy to distinguish malignant lesions from normal tissue or inflammation and in determining the boarders of cancer lesions in surgery. Recent advances in drugs targeting specific tumor receptors, such as AntiBodies (MAB), has created a new demand for developing non-invasive in vivo imaging techniques for detection of cancer biomarkers, and for monitoring their down regulations during therapy. Targeted treatments, combined with new imaging techniques, are expected to potentially result in new imaging and treatment paradigms in cancer therapy. Similar approaches can potentially be applied for the characterization of other disease-related biomarkers. In this chapter, we provide a review of diffuse optical and fluorescence imaging techniques with their application in functional brain imaging and cancer diagnosis. |
| format | Article |
| id | doaj-art-9b04e6e37176474b8994e6853d928398 |
| institution | Kabale University |
| issn | 2210-7177 2210-7185 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-9b04e6e37176474b8994e6853d9283982025-02-03T01:07:59ZengWileyAnalytical Cellular Pathology2210-71772210-71852012-01-01355-631733710.3233/ACP-2012-0058Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In VivoYasaman Ardeshirpour0Amir H. Gandjbakhche1Laleh Najafizadeh2Section on Functional and Analytical Biophotonics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USASection on Functional and Analytical Biophotonics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USASection on Functional and Analytical Biophotonics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USAIn vivo optical imaging is being conducted in a variety of medical applications, including optical breast cancer imaging, functional brain imaging, endoscopy, exercise medicine, and monitoring the photodynamic therapy and progress of neoadjuvant chemotherapy. In the past three decades, in vivo diffuse optical breast cancer imaging has shown promising results in cancer detection, and monitoring the progress of neoadjuvant chemotherapy. The use of near infrared spectroscopy for functional brain imaging has been growing rapidly. In fluorescence imaging, the difference between autofluorescence of cancer lesions compared to normal tissues were used in endoscopy to distinguish malignant lesions from normal tissue or inflammation and in determining the boarders of cancer lesions in surgery. Recent advances in drugs targeting specific tumor receptors, such as AntiBodies (MAB), has created a new demand for developing non-invasive in vivo imaging techniques for detection of cancer biomarkers, and for monitoring their down regulations during therapy. Targeted treatments, combined with new imaging techniques, are expected to potentially result in new imaging and treatment paradigms in cancer therapy. Similar approaches can potentially be applied for the characterization of other disease-related biomarkers. In this chapter, we provide a review of diffuse optical and fluorescence imaging techniques with their application in functional brain imaging and cancer diagnosis.http://dx.doi.org/10.3233/ACP-2012-0058 |
| spellingShingle | Yasaman Ardeshirpour Amir H. Gandjbakhche Laleh Najafizadeh Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo Analytical Cellular Pathology |
| title | Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo |
| title_full | Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo |
| title_fullStr | Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo |
| title_full_unstemmed | Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo |
| title_short | Modern Trends in Imaging IX: Biophotonics Techniques for Structural and Functional Imaging, In Vivo |
| title_sort | modern trends in imaging ix biophotonics techniques for structural and functional imaging in vivo |
| url | http://dx.doi.org/10.3233/ACP-2012-0058 |
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