Reduced Schiff-base derivatives to stop reactive oxygen species production by the Cu(A$\beta $) species: a structure–activity relationship
A${\beta }$ is the peptide involved in Alzheimer’s disease. Its binding to the redox copper ions and the subsequent production of reactive oxygen species (ROS) contributing to the overall oxidative stress observed in the disease is among the deleterious effects A${\beta }$ may have. Here seven reduc...
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Main Authors: | Lefèvre, Margot, Lantigner, Lielou, Andolfo, Laura, Vanucci-Bacqué, Corinne, Benoist, Eric, Esmieu, Charlène, Bedos-Belval, Florence, Hureau, Christelle |
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Format: | Article |
Language: | English |
Published: |
Académie des sciences
2023-10-01
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Series: | Comptes Rendus. Chimie |
Subjects: | |
Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.255/ |
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